| Title: | "Biocidal spray product exposure: Measured gas, particle, and surface concentrations compared with spray model simulations" |
| Author(s): | Clausen PA; Morck TA; Jensen ACO; Schou TW; Kofoed-Sorensen V; Koponen IK; Frederiksen M; Detmer A; Fink M; Norgaard AW; Wolkoff P; |
| Address: | "National Research Centre for the Working Environment, Lerso Parkalle 105, Copenhagen, Denmark. DHI Water Environment Health, Agern Alle 5, Horsholm, Denmark. Scania Sweden AB, Kungens Kurvaleden 3B, Kungens Kurva, Sweden. Force Technolgy, Park Alle 345, Brondby. Novo Nordisk A/S - site Malov, Novo Nordisk Park 1, Malov" |
| DOI: | 10.1080/15459624.2019.1689247 |
| ISSN/ISBN: | 1545-9632 (Electronic) 1545-9624 (Linking) |
| Abstract: | "The purpose of the study was to compare measured air and surface concentrations after application of biocidal spray products with concentrations simulated with the ConsExpo Web spray simulation tool. Three different biocidal spray products were applied in a 20 m(3) climate test chamber with well-controlled environmental conditions (22 +/- 1 degrees C, 50 +/- 2% relative humidity, and air exchange rate of 0.5 h(-1)). The products included an insect spray in a pressurized spray can, another insect spray product, and a disinfectant, the latter two applied separately with the same pumped spray device. The measurements included released particles, airborne organic compounds in both gas and particle phase, and surface concentrations of organic compounds on the wall and floor in front of the spraying position and on the most remote wall. Spraying time was a few seconds and the air concentrations were measured by sampling on adsorbent tubes at 9-13 times points during 4 hr after spraying. The full chamber experiment was repeated 2-3 times for each product. Due to sedimentation the concentrations of the particles in air decayed faster than explained by the air exchange rate. In spite of that, the non-volatile benzalkonium chlorides in the disinfectant could be measured in the air more than 30 min after spraying. ConsExpo Web simulated concentrations that were about half of the measured concentrations of the active substances when as many as possible of the default simulation parameters were replaced by the experimental values. ConsExpo Web was unable to simulate the observed faster decay of the airborne concentrations of the active substances, which might be due to underestimation of the gravitational particle deposition rates. There was a relatively good agreement between measured surface concentrations on the floor and calculated values based on the dislodgeable amount given in the selected ConsExpo Web scenarios. It is suggested to always supplement simulation tool results with practical measurements when assessing the exposure to a spray product" |
| Keywords: | "Aerosols/analysis Disinfectants/*analysis Humans Inhalation Exposure/statistics & numerical data Insecticides/analysis Models, Statistical Occupational Exposure/*statistics & numerical data Aerosols ConsExpo Web disinfectant modeling;" |
| Notes: | "MedlineClausen, Per Axel Morck, Thit Aaroe Jensen, Alexander Christian Osterskov Schou, Torben Wilde Kofoed-Sorensen, Vivi Koponen, Ismo K Frederiksen, Marie Detmer, Ann Fink, Michael Norgaard, Asger W Wolkoff, Peder eng Research Support, Non-U.S. Gov't England 2019/12/10 J Occup Environ Hyg. 2020 Jan; 17(1):15-29. doi: 10.1080/15459624.2019.1689247. Epub 2019 Dec 9" |
