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Ann Epidemiol

Title:		The relationships between ambient air pollutants and childhood asthma and eczema are modified by emotion and conduct problems
Author(s):		Zhou C; Baiz N; Banerjee S; Charpin DA; Caillaud D; de Blay F; Raherison C; Lavaud F; Annesi-Maesano I;
Address:
Journal Title:		Ann Epidemiol
Year:		2013
Volume:		23
Issue:		12
Page Number:		778 - 783
DOI:		10.1016/j.annepidem.2013.09.004
ISSN/ISBN:		1873-2585 (Electronic) 1047-2797 (Linking)
Abstract:		"PURPOSE: This study examined the hypothesis that emotion and conduct problems (ECPs) may modify the relationships between ambient air pollutants and childhood asthma and eczema. METHODS: In the cross-sectional study, 4209 French schoolchildren (aged 10e12 years) were investigated between March 1999 and October 2000. Ambient air pollutants exposures were estimated with dispersion modeling. Health outcomes and ECPs were evaluated by validated questionnaires, completed by the parents. Marginal models were used to analyze the relationships of exposures to ambient air pollutants and/or ECPs to asthma phenotypes and current eczema, adjusting for potential confounders. RESULTS: In our population, interactions were found between ECPs and exposures to ambient air pollutants (benzene, carbon monoxide, nitrogen dioxide, nitrogen oxides, particulate matter with an aerodynamic diameter below 10 mm, volatile organic compounds) (P < .20). In addition, ECPs were related to current wheezing (adjusted prevalence odds ratio [aOR], 2.35; 95% confidence interval [CI], 1.59e3.47), current doctor-diagnosed asthma (aOR, 1.82; 95% CI, 1.25e2.66), and current eczema (aOR, 2.21; 95% CI, 1.61e3.02). Children with ECPs had 1.17e1.51 times higher aORs for the associations between ambient air pollutants and asthma phenotypes and current eczema than those without ECPs. CONCLUSIONS: ECPs may modify the relationships between ambient air pollutants and childhood asthma and eczema"
Keywords:		Air Pollutants/*adverse effects Asthma/epidemiology/*etiology/psychology Benzene/adverse effects Carbon Monoxide/adverse effects Child Child Behavior/psychology Child Behavior Disorders/diagnosis/epidemiology/*psychology Cross-Sectional Studies Eczema/epi;
Notes:		"MedlineZhou, Cailiang Baiz, Nour Banerjee, Soutrik Charpin, Denis Andre Caillaud, Denis de Blay, Frederic Raherison, Chantal Lavaud, Francois Annesi-Maesano, Isabella eng Research Support, Non-U.S. Gov't 2014/01/10 Ann Epidemiol. 2013 Dec; 23(12):778-83. doi: 10.1016/j.annepidem.2013.09.004"