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Ecotoxicol Environ Saf

Title:		"Understanding the inhibitory mechanism of antialgal allelochemical flavonoids from genetic variations: Photosynthesis, toxin synthesis and nutrient utility"
Author(s):		Yu S; Li C; Xu C; Effiong K; Xiao X;
Address:		"Ocean College, Zhejiang University, 310058, Hangzhou, PR China. Ocean College, Zhejiang University, 310058, Hangzhou, PR China; Key Laboratory of Integrated Marine Monitoring and Applied Technologies for Harmful Algal Blooms, S.O.A., MATHAB, Shanghai, PR China. Electronic address: xi@zju.edu.cn"
Journal Title:		Ecotoxicol Environ Saf
Year:		2019
Volume:		20190404
Issue:
Page Number:		18 - 24
DOI:		10.1016/j.ecoenv.2019.03.097
ISSN/ISBN:		1090-2414 (Electronic) 0147-6513 (Linking)
Abstract:		"Flavonoids are natural polyphenolic compounds from plants. As a new biotechnological algaecide, the molecular mechanism of plant flavonoids on the inhibition of Microcystis aeruginosa is still unknown. Therefore, in this study, we analyzed the variation of expressions of photosynthesis-related genes, microcystin synthesis-related genes and the genes involved in N and P acquisition in M. aeruginosa under the flavonoids stress. The results showed that the expression of psbD1, psaB and rbcL related to photosynthesis were influenced by three flavonoids but with different changing tendencies. The transcription of mcyA, mcyD and mcyH related to microcystin synthesis were decreased after 5-d of exposure, which could block microcystin synthesis. Meanwhile, flavonoids treatments resulted in the inhibition of N and P acquisition related genes transcription to affect the absorption of N and P in algal cells, and further influenced the physiological metabolic process of M. aeruginosa"
Keywords:		Flavonoids/metabolism/*pharmacology Genetic Variation Microcystins/genetics/*metabolism Microcystis/*drug effects/genetics/metabolism Nutrients Pheromones/metabolism/*pharmacology *Photosynthesis *Secondary Metabolism Allelopathy Flavonoids Gene transcrip;
Notes:		"MedlineYu, Shumiao Li, Chao Xu, Caicai Effiong, Kokoette Xiao, Xi eng Netherlands 2019/04/07 Ecotoxicol Environ Saf. 2019 Aug 15; 177:18-24. doi: 10.1016/j.ecoenv.2019.03.097. Epub 2019 Apr 4"