| Title: | Serum Periostin Is Negatively Correlated With Exposure to Formaldehyde and Volatile Organic Compounds in Children |
| Author(s): | Yon DK; An J; Ha EK; Jee HM; Izuhara K; Ono J; Jung YH; Lee KS; Sheen YH; Baek H; Han MY; |
| Address: | "Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea. Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan. Research and Development Unit, Shino-Test Corporation, Sagamihara, Japan. Department of Pediatrics, CHA Gangnam Medical Center, CHA University School of Medicine, Seoul, Korea. Department of Pediatrics, Hallym University Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. paviola7@gmail.com. Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea. drmesh@gmail.com" |
| Journal Title: | Allergy Asthma Immunol Res |
| DOI: | 10.4168/aair.2018.10.6.716 |
| ISSN/ISBN: | 2092-7355 (Print) 2092-7363 (Electronic) 2092-7355 (Linking) |
| Abstract: | "Epidemiological studies have shown that exposure to tobacco smoke causing irritation and inflammation in the airways tends to reduce serum periostin concentrations in adults. We now investigate prospective cross-sectional study on 135 Korean students aged 7 years in the first grade who were participating in the Seongnam Atopy Project for Children's Happiness 2016 (SAP(2)(0)(1)(6)) cohort. To the best of our knowledge, this is the first study to show significant inverse correlations between serum periostin concentration and exposure to xylene and formaldehyde in children. Our findings suggested the need for caution in using the serum periostin level as a marker for allergic diseases, since exposure to volatile organic compounds and formaldehyde may confound the interpretation of these results" |
| Keywords: | Periostin children formaldehyde volatile organic compounds; |
| Notes: | "PubMed-not-MEDLINEYon, Dong Keon An, Jaewoo Ha, Eun Kyo Jee, Hye Mi Izuhara, Kenji Ono, Junya Jung, Young Ho Lee, Kyung Suk Sheen, Youn Ho Baek, Heysung Han, Man Yong eng Seongnam Atopy Project for Children's Happiness/ Korea (South) 2018/10/12 Allergy Asthma Immunol Res. 2018 Nov; 10(6):716-721. doi: 10.4168/aair.2018.10.6.716" |
