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Environ Health Perspect

Title:		Recent advances in measuring exhaled breath and estimating exposure and body burden for volatile organic compounds (VOCs)
Author(s):		Wallace LA; Pellizzari ED;
Address:		"Atmospheric Research and Exposure Assessment Laboratory, Warrenton, VA 22091, USA"
Journal Title:		Environ Health Perspect
Year:		1995
Volume:		103 Suppl 3
Issue:		Suppl 3
Page Number:		95 - 98
DOI:		10.1289/ehp.95103s395
ISSN/ISBN:		0091-6765 (Print) 0091-6765 (Linking)
Abstract:		"An improved portable breath measurement method has been developed that allows 1-min sampling times. The equipment has been successfully tested in field and chamber studies. Results of these studies suggest that breath levels following known exposures are predictable and reproducible across a small number of volunteers. The residence times in the body and the distribution in body compartments of several common air toxics have been determined. A simple four-compartment linear model is capable of fitting the observed data. The main parameters of the model include the fraction f of the parent compound exhaled under steady-state conditions and the residence times tau i, in the tau ith compartment. The values of these parameters for several VOCs and for the four body compartments (blood, vessel-rich tissues, vessel-poor tissues, and fat) are provided"
Keywords:		Body Burden *Breath Tests *Environmental Exposure *Environmental Monitoring *Hazardous Substances Humans;
Notes:		"MedlineWallace, L A Pellizzari, E D eng Review 1995/04/01 Environ Health Perspect. 1995 Apr; 103 Suppl 3(Suppl 3):95-8. doi: 10.1289/ehp.95103s395"