| Title: | The plant cell inhibitor KRP6 is involved in multinucleation and cytokinesis disruption in giant-feeding cells induced by root-knot nematodes |
| Author(s): | Vieira P; de Almeida Engler J; |
| Address: | "a Lab. Nematologia/ICAAM-Instituto de Ciencias Agrarias e Ambientais Mediterranicas ; Universidade de Evora ; Nucleo da Mitra ; Evora , Portugal" |
| DOI: | 10.1080/15592324.2015.1010924 |
| ISSN/ISBN: | 1559-2324 (Electronic) 1559-2316 (Print) 1559-2316 (Linking) |
| Abstract: | "The plant cell cycle inhibitor gene KRP6 has been investigated in roots infected by plant-parasitic root-knot nematodes (Meloidogyne spp.). Unexpectedly, KRP6 overexpressing lines revealed a distinct role for this specific KRP as an activator of the mitotic cell cycle. This function was confirmed in Arabidopsis thaliana suspension cultures ectopically expressing KRP6. A blockage in the mitotic exit was observed in cell suspensions and in giant cells resulted in the appearance of multi-nucleated cells. KRP6 expression during nematode infection and the similarity in phenotypes among KRP6 overexpressing cell cultures and giant-cell morphology strongly suggest that KRP6 is involved in multinucleation and acytokinesis occurring in giant-cells. Once again nematodes have been shown to manipulate the plant cell cycle machinery in order to promote gall establishment" |
| Keywords: | "Animals Arabidopsis/*cytology/genetics/metabolism Arabidopsis Proteins/*metabolism Carrier Proteins/*metabolism Cell Size *Cytokinesis Endoreduplication Genes, Plant *Herbivory Mitosis Plant Cells/*metabolism Plant Roots/*parasitology Plant Tumors Ploidie;" |
| Notes: | "MedlineVieira, Paulo de Almeida Engler, Janice eng 2015/04/29 Plant Signal Behav. 2015; 10(4):e1010924. doi: 10.1080/15592324.2015.1010924" |
