| Title: | A review on electronic nose for diagnosis and monitoring treatment response in lung cancer |
| Author(s): | Vadala R; Pattnaik B; Bangaru S; Rai D; Tak J; Kashyap S; Verma U; Yadav G; Dhaliwal RS; Mittal S; Hadda V; Madan K; Guleria R; Agrawal A; Mohan A; |
| Address: | "Center for Advanced Research & Education, Breathomics in Respiratory Diseases, Department of Pulmonary Critical Care & Sleep Medicine, All India Institute of Medical Sciences, New Delhi 110029, India. Division of Non-Communicable Disease, Indian Council for Medical Research, New Delhi, India. Trivedi School of Biosciences, Ashoka University, Sonipat, Haryana 131029, India" |
| ISSN/ISBN: | 1752-7163 (Electronic) 1752-7155 (Linking) |
| Abstract: | "Lung cancer is one of the common malignancies with high mortality rate and a poor prognosis. Most lung cancer cases are diagnosed at an advanced stage either due to limited resources of infrastructure, trained human resources, or delay in clinical suspicion. Low-dose computed tomography has emerged as a screening tool for lung cancer detection but this may not be a feasible option for most developing countries. Electronic nose is a unique non-invasive device that has been developed for lung cancer diagnosis and monitoring response by exhaled breath analysis of volatile organic compounds. The breath-print have been shown to differ not only among lung cancer and other respiratory diseases, but also between various types of lung cancer. Hence, we postulate that the breath-print analysis by electronic nose could be a potential biomarker for the early detection of lung cancer along with monitoring treatment response in a resource-limited setting. In this review, we have consolidated the current published literature suggesting the use of an electronic nose in the diagnosis and monitoring treatment response of lung cancer" |
| Keywords: | Humans Electronic Nose Breath Tests/methods *Lung Neoplasms/diagnostic imaging/therapy Biomarkers/analysis *Volatile Organic Compounds/analysis Exhalation VOCs biomarker eNOSE exhaled breath analysis lung cancer; |
| Notes: | "MedlineVadala, Rohit Pattnaik, Bijay Bangaru, Sunil Rai, Divyanjali Tak, Jaya Kashyap, Seetu Verma, Umashankar Yadav, Geetika Dhaliwal, R S Mittal, Saurabh Hadda, Vijay Madan, Karan Guleria, Randeep Agrawal, Anurag Mohan, Anant eng Research Support, Non-U.S. Gov't Review England 2023/02/01 J Breath Res. 2023 Mar 27; 17(2). doi: 10.1088/1752-7163/acb791" |
