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Front Pharmacol

Title:		"Phytochemistry, Pharmacology and Medicinal Uses of Plants of the Genus Salix: An Updated Review"
Author(s):		Tawfeek N; Mahmoud MF; Hamdan DI; Sobeh M; Farrag N; Wink M; El-Shazly AM;
Address:		"Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany. Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt. Department of Pharmacognosy, Faculty of Pharmacy, Menoufia University, Shibin Elkom, Egypt. AgroBioSciences Research Division, Mohammed VI Polytechnic University, Ben-Guerir, Morocco"
Journal Title:		Front Pharmacol
Year:		2021
Volume:		20210212
Issue:
Page Number:		593856 -
DOI:		10.3389/fphar.2021.593856
ISSN/ISBN:		1663-9812 (Print) 1663-9812 (Electronic) 1663-9812 (Linking)
Abstract:		"The Willows (genus Salix), with more than 330-500 species and 200 hybrids, are trees, shrubs or prostrate plants that are widely distributed in Africa, North America, Europe, and Asia. The genus is traditionally used in folk medicine and represents a valuable source of biologically active compounds among them salicin, a prodrug for salicylic acid. Altogether, 322 secondary metabolites were characterized in the genus including flavonoids 94) (flavonols, flavones, flavanones, isoflavones, flavan-3-ols (catechins and procyanidins), chalcones, dihydrochalcone, anthocyanins, dihydroflavonols), phenolic glycosides (76), organic acids (28), and non-phenolic glycosides (17), sterols and terpenes (17), simple phenolics 13) and lignans 7) in addition to volatiles and fatty acids (69). Furthermore, willows exert analgesic, anti-inflammatory, antioxidant, anticancer, cytotoxic, antidiabetic, antimicrobial, antiobesity, neuroprotective and hepatoprotective activities. The current review provides an updated summary of the importance of willows, their chemical composition and pharmacological activities"
Keywords:		inflammation medicinal and traditional uses pharmacology phytochemistry salix;
Notes:		"PubMed-not-MEDLINETawfeek, Nora Mahmoud, Mona F Hamdan, Dalia I Sobeh, Mansour Farrag, Nawaal Wink, Michael El-Shazly, Assem M eng Review Switzerland 2021/03/02 Front Pharmacol. 2021 Feb 12; 12:593856. doi: 10.3389/fphar.2021.593856. eCollection 2021"