| Title: | Olfactory mechanisms of stereotyped behavior: on the scent of specialized circuits |
| Address: | "Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. stowers@scripps.edu" |
| DOI: | 10.1016/j.conb.2010.02.013 |
| ISSN/ISBN: | 1873-6882 (Electronic) 0959-4388 (Print) 0959-4388 (Linking) |
| Abstract: | "Investigation of how specialized olfactory cues, such as pheromones, are detected has primarily focused on the function of receptor neurons within a subsystem of the nasal cavity, the vomeronasal organ (VNO). Behavioral analyses have long indicated that additional, non-VNO olfactory neurons are similarly necessary for pheromone detection; however, the identity of these neurons has been a mystery. Recent molecular, behavioral, and genomic approaches have led to the identification of multiple atypical sensory circuits that display characteristics suggestive of a specialized function. This review focuses on these non-VNO receptors and neurons, and evaluates their potential for mediating stereotyped olfactory behavior in mammals" |
| Keywords: | Animals Olfactory Mucosa/anatomy & histology/innervation/*physiology Olfactory Nerve/anatomy & histology/*physiology Olfactory Pathways/anatomy & histology/*physiology Pheromones/*physiology Smell/*physiology Stereotyped Behavior/*physiology Vomeronasal O; |
| Notes: | "MedlineStowers, Lisa Logan, Darren W eng R01 DC006885/DC/NIDCD NIH HHS/ R01 DC006885-05/DC/NIDCD NIH HHS/ R01 DC009413/DC/NIDCD NIH HHS/ R01 DC009413-02/DC/NIDCD NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review England 2010/03/27 Curr Opin Neurobiol. 2010 Jun; 20(3):274-80. doi: 10.1016/j.conb.2010.02.013. Epub 2010 Mar 24" |
