| Title: | Identification of the Ubiquitous Antioxidant Tripeptide Glutathione as a Fruit Fly Semiochemical |
| Author(s): | Cheseto X; Kachigamba DL; Ekesi S; Ndung'u M; Teal PEA; Beck JJ; Torto B; |
| Address: | "International Centre of Insect Physiology and Ecology (icipe), P.O. Box 30772-00100, Nairobi, Kenya. Chemistry Department, Jomo Kenyatta University of Agriculture and Technology , P.O. Box 62000-00200 Nairobi, Kenya. Department of Agricultural Research Services, Bvumbwe Research Station , P.O. Box 5748, Limbe, Malawi. Chemistry Research Unit, Center for Medical, Agricultural and Veterinary Entomology, Agricultural Research Service, U.S. Department of Agriculture , 1700 Southwest 23rd Drive, Gainesville, Florida 32608, United States" |
| ISSN/ISBN: | 1520-5118 (Electronic) 0021-8561 (Linking) |
| Abstract: | "Many insects mark their oviposition sites with a host marking pheromone (HMP) to deter other females from overexploiting these sites. Previous studies have identified and used HMPs to manage certain fruit fly species; however, few are known for African indigenous fruit flies. The HMP of the African fruit fly, Ceratitis cosyra, was identified as the ubiquitous plant and animal antioxidant tripeptide, glutathione (GSH). GSH was isolated from the aqueous extract of adult female fecal matter and characterized by LC-QTOF-MS. GSH level increased with increasing age of female fecal matter, with highest concentration detected from 2-week-old adult females. Additionally, GSH levels were 5-10-times higher in fecal matter than in the ovipositor or hemolymph extracts of females. In bioassays, synthetic GSH reduced oviposition responses in conspecifics of C. cosyra and the heterospecific species C. rosa, C. fasciventris, C. capitata, and Zeugodacus cucurbitae. These results represent the first report of a ubiquitous antioxidant as a semiochemical in insects and its potential use in fruit fly management" |
| Keywords: | Animals Antioxidants/*analysis Ceratitis capitata/chemistry Feces/chemistry Female Glutathione/*analysis Insect Control/methods Oviposition Pheromones/*analysis Tephritidae/*chemistry Time Factors Ceratitis cosyra fruit fly host marking pheromone oviposit; |
| Notes: | "MedlineCheseto, Xavier Kachigamba, Donald L Ekesi, Sunday Ndung'u, Mary Teal, Peter E A Beck, John J Torto, Baldwyn eng 2017/09/16 J Agric Food Chem. 2017 Oct 4; 65(39):8560-8568. doi: 10.1021/acs.jafc.7b03164. Epub 2017 Sep 25" |
