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Trends Genet

Title:		"Signal transduction in yeast mating: receptors, transcription factors, and the kinase connection"
Author(s):		Sprague GF;
Address:		"Institute of Molecular Biology, University of Oregon, Eugene 97403"
Journal Title:		Trends Genet
Year:		1991
Volume:		7
Issue:		11-Dec
Page Number:		393 - 398
DOI:
ISSN/ISBN:		0168-9525 (Print) 0168-9525 (Linking)
Abstract:		"In the yeast Saccharomyces cerevisiae, peptide mating pheromones activate a signal transduction pathway that leads to cellular differentiation and cell division cycle arrest. It is now possible to trace the major events of this pathway. binding of pheromone to G-protein-coupled receptors activates a cascade of serine/threonine protein kinases that ultimately phosphorylate and increase the activity of an identified transcription factor"
Keywords:		"Cell Cycle/physiology Cell Nucleus/physiology GTP-Binding Proteins/physiology Gene Expression Regulation, Fungal Genes, Fungal Mating Factor Peptides/genetics/metabolism Phosphorylation Protein Kinases/physiology Protein Processing, Post-Translational Pro;"
Notes:		"MedlineSprague, G F Jr eng Review England 1991/11/11 Trends Genet. 1991 Nov-Dec; 7(11-12):393-8"