| Title: | Review: Effect of essential fatty acids and conjugated linoleic acid on the adaptive physiology of dairy cows during the transition period |
| Author(s): | Veshkini A; Ceciliani F; Bonnet M; Hammon HM; |
| Address: | "Institute of Nutritional Physiology Research, Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany; Institute of Animal Science, Physiology Unit, University of Bonn, 53115 Bonn, Germany; Department of Veterinary Medicine, Universita degli Studi di Milano, 26900 Lodi, Italy. Electronic address: veshkini@fbn-dummerstorf.de. Department of Veterinary Medicine, Universita degli Studi di Milano, 26900 Lodi, Italy. INRAE, Universite Clermont Auvergne, VetAgro Sup, UMR Herbivores, F-63122 Saint-Genes-Champanelle, France. Institute of Nutritional Physiology Research, Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany" |
| DOI: | 10.1016/j.animal.2023.100757 |
| ISSN/ISBN: | 1751-732X (Electronic) 1751-7311 (Linking) |
| Abstract: | "Cows fed total mixed rations (silage-based) may not receive as much essential fatty acids (EFAs) and conjugated linoleic acids (CLAs) as cows fed pasture-based rations (fresh grass) containing rich sources of polyunsaturated fatty acids. CLA-induced milk fat depression allows dairy cows to conserve more metabolisable energy, thereby shortening the state of negative energy balance and reducing excessive fat mobilisation at early lactation. EFAs, particularly alpha-linolenic acid, exert anti-inflammatory and antioxidative properties, thereby modulating immune functions. Thus, combined EFA and CLA supplementation seems to be an effective nutritional strategy to relieve energy metabolism and to improve immune response, which are often compromised during the transition from late pregnancy to lactation in high-yielding dairy cows. There has been extensive research on this idea over the last two decades, and despite promising results, several interfering factors have led to varying findings, making it difficult to conclude whether and under what conditions EFA and CLA supplementations are beneficial for dairy cows during the transition period. This article reviews the latest studies on the effects of EFA and CLA supplementation, alone or in combination, on dairy cow metabolism and health during various stages around parturition. Our review article summarises and provides novel insights into the mechanisms by which EFA and/or CLA influence markers of metabolism, energy homeostasis and partitioning, immunity, and inflammation revealed by a deep molecular phenotyping" |
| Keywords: | "Female Cattle Pregnancy Animals *Dietary Supplements Diet/veterinary *Linoleic Acids, Conjugated/pharmacology Milk/metabolism Lactation/physiology Fatty Acids, Essential/metabolism/pharmacology Fatty Acids/metabolism Energy balance Immunity Lactation Meta;" |
| Notes: | "MedlineVeshkini, Arash Ceciliani, Fabrizio Bonnet, Muriel Hammon, Harald Michael eng Review England 2023/03/26 Animal. 2023 Jun; 17 Suppl 2:100757. doi: 10.1016/j.animal.2023.100757. Epub 2023 Mar 7" |
