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Clin Chim Acta

Title:		VOC breath biomarkers in lung cancer
Author(s):		Saalberg Y; Wolff M;
Address:		"Hamburg University of Applied Sciences, Heinrich Blasius Institute for Physical Technologies, Berliner Tor 21, 20099 Hamburg, Germany. Electronic address: yannick.saalberg@haw-hamburg.de. Hamburg University of Applied Sciences, Heinrich Blasius Institute for Physical Technologies, Berliner Tor 21, 20099 Hamburg, Germany"
Journal Title:		Clin Chim Acta
Year:		2016
Volume:		20160521
Issue:
Page Number:		5 - 9
DOI:		10.1016/j.cca.2016.05.013
ISSN/ISBN:		1873-3492 (Electronic) 0009-8981 (Linking)
Abstract:		"This review provides an overview of volatile organic compounds (VOCs) which are considered lung cancer biomarkers for diagnostic breath analysis. It includes results of scientific publications from 1985 to 2015. The identified VOCs are listed and ranked according to their occurrence of nomination. The applied detection and sampling methods are specified but not evaluated. Possible reasons for the different results of the studies are stated. Among the most frequently emerging biomarkers are 2-butanone and 1-propanol as well as isoprene, ethylbenzene, styrene and hexanal. The outcome of this review may be helpful for the development of a lung cancer screening device"
Keywords:		"Biomarkers, Tumor/*analysis *Breath Tests Humans Lung Neoplasms/*diagnosis Respiration Volatile Organic Compounds/*analysis Biomarker Breath analysis Diagnostics Lung cancer Screening Voc;"
Notes:		"MedlineSaalberg, Yannick Wolff, Marcus eng Review Netherlands 2016/05/26 Clin Chim Acta. 2016 Aug 1; 459:5-9. doi: 10.1016/j.cca.2016.05.013. Epub 2016 May 21"