Title: | "PkpA, a novel Phycomyces blakesleeanus serine/threonine protein kinase" |
Author(s): | Ruiz-Perez VL; Murillo FJ; Torres-Martinez S; |
Address: | "Departamento de Genetica y Microbiologia, Facultad de Biologia, Universidad de Murcia, Spain" |
ISSN/ISBN: | 0172-8083 (Print) 0172-8083 (Linking) |
Abstract: | "This work reports the cloning and sequencing of pkpA, a gene of the filamentous fungus Phycomyces blakesleeanus, whose expression seems to be coupled to vegetative growth. This gene encodes a putative serine/threonine-specific protein kinase, whose sequence is related to that of the yeast protein STE20, involved in pheromone-response pathways, and to a number of MAPK kinase proteins. However, detailed analysis of the kinase sequence suggests that PkpA is a novel serine/threonine protein kinase that probably participates as an intermediate in an intracellular system controlling nuclear proliferation in P. blakesleeanus" |
Keywords: | "Amino Acid Sequence Base Sequence Binding Sites Cell Division Cloning, Molecular Conserved Sequence/genetics DNA Primers Fungal Proteins/chemistry Gene Expression Regulation, Fungal Genes, Fungal Introns/genetics Molecular Sequence Data Phycomyces/enzymol;" |
Notes: | "MedlineRuiz-Perez, V L Murillo, F J Torres-Martinez, S eng Research Support, Non-U.S. Gov't 1995/09/01 Curr Genet. 1995 Sep; 28(4):309-16. doi: 10.1007/BF00326428" |