| Title: | Strategies in herbivory by mammals revisited: The role of liver metabolism in a juniper specialist (Neotoma stephensi) and a generalist (Neotoma albigula) |
| Author(s): | Orr TJ; Kitanovic S; Schramm KM; Skopec MM; Wilderman PR; Halpert JR; Dearing MD; |
| Address: | "School of Biological Sciences, University of Utah, Salt Lake City, UT, USA. Department of Botany, Weber State University, Ogden, UT, USA. Department of Zoology, Weber State University, Ogden, UT, USA. School of Pharmacy, University of Connecticut, Storrs, CT, USA" |
| ISSN/ISBN: | 1365-294X (Electronic) 0962-1083 (Linking) |
| Abstract: | "Although herbivory is widespread among mammals, few species have adopted a strategy of dietary specialization. Feeding on a single plant species often exposes herbivores to high doses of plant secondary metabolites (PSMs), which may exceed the animal's detoxification capacities. Theory predicts that specialists will have unique detoxification mechanisms to process high levels of dietary toxins. To evaluate this hypothesis, we compared liver microsomal metabolism of a juniper specialist, Neotoma stephensi (diet >85% juniper), to a generalist, N. albigula (diet |
| Keywords: | Animals *Herbivory *Juniperus Liver/*metabolism Sigmodontinae/classification/*metabolism Neotoma biotransformation diet switching enzyme assay herbivory mammalian herbivores metabolism terpenes trade-offs woodrat; |
| Notes: | "MedlineOrr, Teri J Kitanovic, Smiljka Schramm, Katharina M Skopec, Michele M Wilderman, P Ross Halpert, James R Dearing, M Denise eng Research Support, U.S. Gov't, Non-P.H.S. England 2020/04/05 Mol Ecol. 2020 May; 29(9):1674-1683. doi: 10.1111/mec.15431. Epub 2020 Apr 22" |
