Title: | Saccharomyces cerevisiae alpha-factor prevents formation of glycoproteins in a cells |
Author(s): | Orlean P; Seebacher G; Tanner W; |
DOI: | 10.1016/0014-5793(83)80588-2 |
ISSN/ISBN: | 0014-5793 (Print) 0014-5793 (Linking) |
Abstract: | alpha-Factor inhibits incorporation of [14C]glucosamine into water-soluble and into SDS-extractable glycoproteins to about 90%. The incorporation into chitin is not affected and the same is true for [14C]phenylalanine incorporation into protein. The inhibition of glycoprotein synthesis is specific for a cells |
Keywords: | Glucosamine/metabolism Glucose/metabolism Glycoproteins/*biosynthesis Mannose/metabolism Mating Factor Peptides/*pharmacology Phenylalanine/metabolism Saccharomyces cerevisiae/*metabolism Solubility; |
Notes: | "MedlineOrlean, P Seebacher, G Tanner, W eng Research Support, Non-U.S. Gov't England 1983/07/25 FEBS Lett. 1983 Jul 25; 158(2):247-51. doi: 10.1016/0014-5793(83)80588-2" |