| Title: | Recent Advances in Behavioral (Epi)Genetics in Eusocial Insects |
| Author(s): | Opachaloemphan C; Yan H; Leibholz A; Desplan C; Reinberg D; |
| Address: | "Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA; email: comzit.opachaloemphan@med.nyu.edu , danny.reinberg@nyumc.org. Department of Biology, University of Florida, Gainesville, Florida 32611, USA; email: hua.yan@ufl.edu. Howard Hughes Medical Institute, New York University School of Medicine, New York, NY 10016, USA. Department of Biology, New York University, New York, NY 10003, USA; email: al5260@nyu.edu , cd38@nyu.edu" |
| DOI: | 10.1146/annurev-genet-120116-024456 |
| ISSN/ISBN: | 1545-2948 (Electronic) 0066-4197 (Print) 0066-4197 (Linking) |
| Abstract: | "Eusocial insects live in societies in which distinct family members serve specific roles in maintaining the colony and advancing the reproductive ability of a few select individuals. Given the genetic similarity of all colony members, the diversity of morphologies and behaviors is surprising. Social communication relies on pheromones and olfaction, as shown by mutants of orco, the universal odorant receptor coreceptor, and through electrophysiological analysis of neuronal responses to pheromones. Additionally, neurohormonal factors and epigenetic regulators play a key role in caste-specific behavior, such as foraging and caste switching. These studies start to allow an understanding of the molecular mechanisms underlying social behavior and provide a technological foundation for future studies of eusocial insects. In this review, we highlight recent findings in eusocial insects that advance our understanding of genetic and epigenetic regulations of social behavior and provide perspectives on future studies using cutting-edge technologies" |
| Keywords: | "Animals Behavior, Animal/*physiology Epigenesis, Genetic/*genetics/physiology Insecta/*genetics/physiology Neurons/metabolism Pheromones/genetics Receptors, Odorant/genetics Smell/genetics *Social Behavior caste development critical periods epigenetics ne;" |
| Notes: | "MedlineOpachaloemphan, Comzit Yan, Hua Leibholz, Alexandra Desplan, Claude Reinberg, Danny eng F32 AG044971/AG/NIA NIH HHS/ R01 AG058762/AG/NIA NIH HHS/ R01 EY013010/EY/NEI NIH HHS/ 2009005/HHMI/Howard Hughes Medical Institute/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review 2018/09/13 Annu Rev Genet. 2018 Nov 23; 52:489-510. doi: 10.1146/annurev-genet-120116-024456. Epub 2018 Sep 12" |
