| Title: | "Production of (5R,6S)-6-acetoxy-5-hexadecanolide, the mosquito oviposition pheromone, from the seed oil of the summer cypress plant, Kochia scoparia (Chenopodiaceae)" |
| Author(s): | Olagbemiro TO; Birkett MA; Mordue AJ; Pickett JA; |
| Address: | "Department of Chemistry, Abubakar Tafawa Balewa University, Bauchi, Nigeria" |
| ISSN/ISBN: | 0021-8561 (Print) 0021-8561 (Linking) |
| Abstract: | "The oviposition pheromone for the pathogen-vectoring mosquitoes in the genus Culex (Diptera: Culicidae), that is, (5R, 6S)-6-acetoxy-5-hexadecanolide, is efficiently synthesized, in admixture with the inactive (5S,6R) enantiomer ( approximately 33% w/w), from the fixed oil extracted from the seeds of the summer cypress plant, Kochia scoparia (Chenopodiaceae), cultivated on an industrial scale. Oviposition bioassays using gravid females of Culex quinquefasciatus, a vector of filariasis in human beings, showed that the product was attractive, with activity comparable to that of a pure synthetic sample containing the same amount of the active enantiomer. Production of the pheromone in the form of a biologically active crude material via a cheap and renewable plant suitable for development as a new industrial crop provides the basis for control of Cx. quinquefasciatus and other congeneric vectors of pathogens in resource-poor areas of the world" |
| Keywords: | Animals Biological Assay *Chenopodiaceae Culex/*physiology Female Humans Insect Vectors Molecular Structure Oviposition/*drug effects Pheromones/*biosynthesis/isolation & purification/pharmacology Plant Oils/*chemistry Pyrones/isolation & purification/*me; |
| Notes: | "MedlineOlagbemiro, T O Birkett, M A Mordue (Luntz), A J (Luntz) Pickett, J A eng Research Support, Non-U.S. Gov't 1999/12/20 J Agric Food Chem. 1999 Aug; 47(8):3411-5. doi: 10.1021/jf990294b" |
