| Title: | [The pattern of major urinary proteins (MUPS) expression during postnatal ontogenesis of a laboratory mouse depends on genotype and sex] |
| Author(s): | Novikov SN; Churakov GA; Filimonenko AA; Ermakova II; Fedorova EM; Burkot IA; |
| ISSN/ISBN: | 0475-1450 (Print) 0475-1450 (Linking) |
| Abstract: | "We investigated the specific pattern of major urinary proteins (MUPs) expression in 3-, 4-, and 12-week old mice of CBA/LacY and C57BL/6JY inbred strains using polyacrylamide gel electrophoresis. Quantitative evaluation of 8 protein fractions A-H with regard to sex, age, and genotype of the animals is presented for the first time. Actual problems of genetic control and neuroendocrine regulation of MUPs expression during ontogenesis are discussed. In the light of current views on MUPs as a key component in intrapopulation information exchange via pheromones, we put forward the idea that the genetically determined structure of the olfactory code of the definitive type is formed at an early ontogenetic stage on the basis of the MUPs combinatorial pattern" |
| Keywords: | "Aging Animals Female Genotype Male Mice Mice, Inbred C57BL Mice, Inbred CBA Proteins/genetics/*metabolism Sex Factors Species Specificity;" |
| Notes: | "MedlineNovikov, S N Churakov, G A Filimonenko, A A Ermakova, I I Fedorova, E M Burkot, I A rus English Abstract Russia (Federation) 2009/08/27 Ontogenez. 2009 Jul-Aug; 40(4):261-9" |
