Bedoukian   RussellIPM   RussellIPM   Piezoelectric Micro-Sprayer


Home
Animal Taxa
Plant Taxa
Semiochemicals
Floral Compounds
Semiochemical Detail
Semiochemicals & Taxa
Synthesis
Control
Invasive spp.
References

Abstract

Guide

Alphascents
Pherobio
InsectScience
E-Econex
Counterpart-Semiochemicals
Print
Email to a Friend
Kindly Donate for The Pherobase

« Previous Abstract"Ultrasonic courtship song in the Asian corn borer moth, Ostrinia furnacalis"    Next AbstractOptimizing the Distillation of Greek Oregano-Do Process Parameters Affect Bioactive Aroma Constituents and In Vitro Antioxidant Activity? »

J Chromatogr A


Title:Rapid and efficient purification of positron emission tomography probes by hydrophilic interaction chromatography
Author(s):Nakao R; Ito T; Hayashi K; Fukumura T; Suzuki K;
Address:"Molecular Imaging Center, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan. nakaor@nirs.go.jp"
Journal Title:J Chromatogr A
Year:2009
Volume:20090313
Issue:18
Page Number:3933 - 3940
DOI: 10.1016/j.chroma.2009.03.012
ISSN/ISBN:1873-3778 (Electronic) 0021-9673 (Linking)
Abstract:"A rapid and efficient preparative high-performance liquid chromatographic procedure was established to purify short-lived positron emission tomography radio-probes. This method is based on hydrophilic interaction chromatography utilizing a semi-preparative silica column (10 mm I.D.) and a high volatile organic mobile phase (>90% acetonitrile). In nine different radiopharmaceuticals studied, six compounds could be separated from the unlabeled precursor with good resolution and faster elution than its precursor. These characteristics enabled significant shortening of the separation and evaporation processes in the manufacture of short-lived radiopharmaceuticals. Several (11)C-radiopharmaceuticals could be prepared within one half-life of carbon-11 (20.4 min), including radiosynthesis, purification and formulation steps with sufficient radiochemical/chemical purity and high levels of radioactivity/specific radioactivity"
Keywords:"Carbon Radioisotopes/chemistry/*isolation & purification Chromatography, High Pressure Liquid/*methods *Electrons Half-Life Positron-Emission Tomography/*instrumentation Radiopharmaceuticals/chemistry/*isolation & purification;"
Notes:"MedlineNakao, Ryuji Ito, Takehito Hayashi, Kazutaka Fukumura, Toshimitsu Suzuki, Kazutoshi eng Evaluation Study Netherlands 2009/03/25 J Chromatogr A. 2009 May 1; 1216(18):3933-40. doi: 10.1016/j.chroma.2009.03.012. Epub 2009 Mar 13"

 
Back to top
 
Citation: El-Sayed AM 2024. The Pherobase: Database of Pheromones and Semiochemicals. <http://www.pherobase.com>.
© 2003-2024 The Pherobase - Extensive Database of Pheromones and Semiochemicals. Ashraf M. El-Sayed.
Page created on 25-12-2024