| Title: | Role of clothing in both accelerating and impeding dermal absorption of airborne SVOCs |
| Author(s): | Morrison GC; Weschler CJ; Beko G; Koch HM; Salthammer T; Schripp T; Toftum J; Clausen G; |
| Address: | "Civil, Architectural and Environmental Engineering, Missouri University of Science and Technology, Rolla, Missouri, USA. Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA. Department of Civil Engineering, International Centre for Indoor Environment and Energy, Technical University of Denmark, Lyngby, Denmark. Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universitat Bochum (IPA), Burkle-de-la-Camp-Platz 1, Bochum, Germany. Department of Material Analysis and Indoor Chemistry, Fraunhofer WKI, Bienroder Weg 54E, Braunschweig, Germany" |
| Journal Title: | J Expo Sci Environ Epidemiol |
| ISSN/ISBN: | 1559-064X (Electronic) 1559-0631 (Linking) |
| Abstract: | "To assess the influence of clothing on dermal uptake of semi-volatile organic compounds (SVOCs), we measured uptake of selected airborne phthalates for an individual wearing clean clothes or air-exposed clothes and compared these results with dermal uptake for bare-skinned individuals under otherwise identical experimental conditions. Using a breathing hood to isolate dermal from inhalation uptake, we measured urinary metabolites of diethylphthalate (DEP) and di-n-butylphthalate (DnBP) from an individual exposed to known concentrations of these compounds for 6 h in an experimental chamber. The individual wore either clean (fresh) cotton clothes or cotton clothes that had been exposed to the same chamber air concentrations for 9 days. For a 6-h exposure, the net amounts of DEP and DnBP absorbed when wearing fresh clothes were, respectively, 0.017 and 0.007 mug/kg/(mug/m(3)); for exposed clothes the results were 0.178 and 0.261 mug/kg/(mug/m(3)), respectively (values normalized by air concentration and body mass). When compared against the average results for bare-skinned participants, clean clothes were protective, whereas exposed clothes increased dermal uptake for DEP and DnBP by factors of 3.3 and 6.5, respectively. Even for non-occupational environments, wearing clothing that has adsorbed/absorbed indoor air pollutants can increase dermal uptake of SVOCs by substantial amounts relative to bare skin" |
| Keywords: | "Air Pollutants/*analysis/*urine Air Pollution, Indoor/*analysis *Clothing Denmark Environmental Monitoring Humans Male Middle Aged Risk Assessment *Skin Absorption Volatile Organic Compounds/*urine;" |
| Notes: | "MedlineMorrison, Glenn C Weschler, Charles J Beko, Gabriel Koch, Holger M Salthammer, Tunga Schripp, Tobias Toftum, Jorn Clausen, Geo eng 2015/06/11 J Expo Sci Environ Epidemiol. 2016 Jan-Feb; 26(1):113-8. doi: 10.1038/jes.2015.42. Epub 2015 Jun 10" |
