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Int J Environ Res Public Health

Title:		A Review of Volatile Organic Compound Contamination in Post-Industrial Urban Centers: Reproductive Health Implications Using a Detroit Lens
Author(s):		Miller CJ; Runge-Morris M; Cassidy-Bushrow AE; Straughen JK; Dittrich TM; Baker TR; Petriello MC; Mor G; Ruden DM; O'Leary BF; Teimoori S; Tummala CM; Heldman S; Agarwal M; Roth K; Yang Z; Baker BB;
Address:		"Center for Leadership in Environmental Awareness and Research (CLEAR)-Integrative Biosciences Center, Wayne State University, 6135 Woodward Ave, Detroit, MI 48202, USA. Department of Civil and Environmental Engineering-College of Engineering, Wayne State University, 5050 Anthony Wayne Drive, Detroit, MI 48202, USA. Institute of Environmental Health Sciences-Integrative Biosciences Center, Wayne State University, 6135 Woodward Ave, Detroit, MI 48202, USA. Department of Public Health Sciences, Henry Ford Hospital, 1 Ford Place, Detroit, MI 48202, USA. Department of Pharmacology-School of Medicine, Wayne State University, 540 E. Canfield, Detroit, MI 48202, USA. C.S. Mott Center for Human Growth and Development, Wayne State University, 275 E. Hancock, Detroit, MI 48201, USA. Department of Obstetrics and Gynecology, Wayne State University, 275 E. Hancock, Detroit, MI 48201, USA"
Journal Title:		Int J Environ Res Public Health
Year:		2020
Volume:		20201125
Issue:		23
Page Number:		-
DOI:		10.3390/ijerph17238755
ISSN/ISBN:		1660-4601 (Electronic) 1661-7827 (Print) 1660-4601 (Linking)
Abstract:		"Volatile organic compounds (VOCs) are a group of aromatic or chlorinated organic chemicals commonly found in manufactured products that have high vapor pressure, and thus vaporize readily at room temperature. While airshed VOCs are well studied and have provided insights into public health issues, we suggest that belowground VOCs and the related vapor intrusion process could be equally or even more relevant to public health. The persistence, movement, remediation, and human health implications of subsurface VOCs in urban landscapes remain relatively understudied despite evidence of widespread contamination. This review explores the state of the science of subsurface movement and remediation of VOCs through groundwater and soils, the linkages between these poorly understood contaminant exposure pathways and health outcomes based on research in various animal models, and describes the role of these contaminants in human health, focusing on birth outcomes, notably low birth weight and preterm birth. Finally, this review provides recommendations for future research to address knowledge gaps that are essential for not only tackling health disparities and environmental injustice in post-industrial cities, but also protecting and preserving critical freshwater resources"
Keywords:		"Animals Cities *Environmental Exposure/statistics & numerical data Female *Groundwater/chemistry Humans Infant, Low Birth Weight Infant, Newborn Michigan Pregnancy Premature Birth *Reproductive Health/statistics & numerical data *Soil Pollutants/analysis;"
Notes:		"MedlineMiller, Carol J Runge-Morris, Melissa Cassidy-Bushrow, Andrea E Straughen, Jennifer K Dittrich, Timothy M Baker, Tracie R Petriello, Michael C Mor, Gil Ruden, Douglas M O'Leary, Brendan F Teimoori, Sadaf Tummala, Chandra M Heldman, Samantha Agarwal, Manisha Roth, Katherine Yang, Zhao Baker, Bridget B eng UH3 OD023285/OD/NIH HHS/ UL1 TR001863/TR/NCATS NIH HHS/ P30 ES020957/ES/NIEHS NIH HHS/ UG3 OD023285/OD/NIH HHS/ R01 AI145829/AI/NIAID NIH HHS/ R00 ES028734/ES/NIEHS NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review Switzerland 2020/12/02 Int J Environ Res Public Health. 2020 Nov 25; 17(23):8755. doi: 10.3390/ijerph17238755"