| Title: | Silver(i)-catalyzed sequential hydroamination and Prins type cyclization for the synthesis of fused benzo-delta-sultams |
| Author(s): | Maheshwar Rao B; Yadav JS; Sridhar B; Subba Reddy BV; |
| Address: | "Centre for Semiochemicals, CSIR-Indian Institute of Chemical Technology, Hyderabad-500 007, India. basireddy@iict.res.in" |
| ISSN/ISBN: | 1477-0539 (Electronic) 1477-0520 (Linking) |
| Abstract: | "An intramolecular annulation strategy has been developed for the synthesis of tetrahydrobenzo[e]pyrano[4,3-c][1,2]thiazine derivatives by means of coupling of aldehydes with 2-(4-hydroxybut-1-yn-1-yl)-N-arylsulfonamides using a catalytic amount of silver hexafluoroantimonate in toluene at 80 degrees C. This is the first report on the synthesis of fused benzo-delta-sultam derivatives through C-N, C-O, and C-C bond formations. The reaction proceeds through a cascade of hydroamination and Prins type cyclization" |
| Notes: | "PubMed-not-MEDLINEMaheshwar Rao, B Yadav, J S Sridhar, B Subba Reddy, B V eng Research Support, Non-U.S. Gov't England 2018/07/03 Org Biomol Chem. 2018 Jul 18; 16(28):5163-5166. doi: 10.1039/c8ob00918j" |
