« Previous AbstractSpatial and temporal organization of ensemble representations for different odor classes in the moth antennal lobe    Next Abstract"Toluene decomposition by non-thermal plasma assisted CoO(x) - gamma-Al(2)O(3): The relative contributions of specific energy input of plasma, Co(3+) and oxygen vacancy" »

J Comp Physiol A Neuroethol Sens Neural Behav Physiol

Title:		Responses of protocerebral neurons in Manduca sexta to sex-pheromone mixtures
Author(s):		Lei H; Chiu HY; Hildebrand JG;
Address:		"Department of Neuroscience, University of Arizona, Tucson, AZ, 85721, USA, hlei@email.arizona.edu"
Journal Title:		J Comp Physiol A Neuroethol Sens Neural Behav Physiol
Year:		2013
Volume:		20130822
Issue:		11
Page Number:		997 - 1014
DOI:		10.1007/s00359-013-0844-4
ISSN/ISBN:		1432-1351 (Electronic) 0340-7594 (Print) 0340-7594 (Linking)
Abstract:		"Male Manduca sexta moths are attracted to a mixture of two components of the female's sex pheromone at the natural concentration ratio. Deviation from this ratio results in reduced attraction. Projection neurons innervating prominent male-specific glomeruli in the male's antennal lobe produce maximal synchronized spiking activity in response to synthetic mixtures of the two components centering around the natural ratio, suggesting that behaviorally effective mixture ratios are encoded by synchronous neuronal activity. We investigated the physiological activity and morphology of downstream protocerebral neurons that responded to antennal stimulation with single pheromone components and their mixtures at various concentration ratios. Among the tested neurons, only a few gave stronger responses to the mixture at the natural ratio whereas most did not distinguish among the mixtures that were tested. We also found that the population response distinguished among the two pheromone components and their mixtures, prior to the peak population response. This observation is consistent with our previous finding that synchronous firing of antennal-lobe projection neurons reaches its maximum before the firing rate reaches its peak. Moreover, the response patterns of protocerebral neurons are diverse, suggesting that the representation of olfactory stimuli at the level of protocerebrum is complex"
Keywords:		"Action Potentials/*drug effects Animals Brain/*cytology Brain Mapping Dose-Response Relationship, Drug Drug Combinations Electric Stimulation Fluorescent Dyes/metabolism Functional Laterality Male Manduca Neurons/*drug effects *Odorants Olfactory Pathways;Neuroscience;"
Notes:		"MedlineLei, Hong Chiu, Hong-Yan Hildebrand, John G eng R01 DC002751/DC/NIDCD NIH HHS/ R01-DC02751/DC/NIDCD NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Germany 2013/08/27 J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2013 Nov; 199(11):997-1014. doi: 10.1007/s00359-013-0844-4. Epub 2013 Aug 22"