| Title: | Taste and pheromonal inputs govern the regulation of time investment for mating by sexual experience in male Drosophila melanogaster |
| Author(s): | Lee SG; Sun D; Miao H; Wu Z; Kang C; Saad B; Nguyen KH; Guerra-Phalen A; Bui D; Abbas AH; Trinh B; Malik A; Zeghal M; Auge AC; Islam ME; Wong K; Stern T; Lebedev E; Sherratt TN; Kim WJ; |
| Address: | "Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Canada. The HIT Center for Life Sciences, Harbin Institute of Technology, Harbin, China. Department of Agricultural Biotechnology, Seoul National University, Seoul, South Korea. Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, South Korea. Department of Biology, Carleton University, Ottawa, Canada" |
| DOI: | 10.1371/journal.pgen.1010753 |
| ISSN/ISBN: | 1553-7404 (Electronic) 1553-7390 (Print) 1553-7390 (Linking) |
| Abstract: | "Males have finite resources to spend on reproduction. Thus, males rely on a 'time investment strategy' to maximize their reproductive success. For example, male Drosophila melanogaster extends their mating duration when surrounded by conditions enriched with rivals. Here we report a different form of behavioral plasticity whereby male fruit flies exhibit a shortened duration of mating when they are sexually experienced; we refer to this plasticity as 'shorter-mating-duration (SMD)'. SMD is a plastic behavior and requires sexually dimorphic taste neurons. We identified several neurons in the male foreleg and midleg that express specific sugar and pheromone receptors. Using a cost-benefit model and behavioral experiments, we further show that SMD behavior exhibits adaptive behavioral plasticity in male flies. Thus, our study delineates the molecular and cellular basis of the sensory inputs required for SMD; this represents a plastic interval timing behavior that could serve as a model system to study how multisensory inputs converge to modify interval timing behavior for improved adaptation" |
| Keywords: | "Animals Male *Drosophila melanogaster/genetics *Pheromones Taste Sexual Behavior, Animal/physiology Reproduction Drosophila;" |
| Notes: | "MedlineLee, Seung Gee Sun, Dongyu Miao, Hongyu Wu, Zekun Kang, Changku Saad, Baraa Nguyen, Khoi-Nguyen Ha Guerra-Phalen, Adrian Bui, Dorothy Abbas, Al-Hassan Trinh, Brian Malik, Ashvent Zeghal, Mahdi Auge, Anne-Christine Islam, Md Ehteshamul Wong, Kyle Stern, Tiffany Lebedev, Elizabeth Sherratt, Thomas N Kim, Woo Jae eng Research Support, Non-U.S. Gov't 2023/05/22 PLoS Genet. 2023 May 22; 19(5):e1010753. doi: 10.1371/journal.pgen.1010753. eCollection 2023 May" |
