| Title: | Controlled Lactonization of o-Coumaric Esters Mediated by Supramolecular Gels |
| Author(s): | Cenciarelli F; Falini G; Giuri D; Tomasini C; |
| Address: | "Dipartimento di Chimica Giacomo Ciamician, Universita di Bologna, Via Selmi, 2, 40126 Bologna, Italy" |
| ISSN/ISBN: | 2310-2861 (Electronic) 2310-2861 (Linking) |
| Abstract: | "Fragrances are volatile organic compounds widely used in our daily life. Unfortunately, the high volatility required to reach human receptors reduces their persistency in the air. To contrast this effect, several strategies may be used. Among them, we present here the combination of two techniques: the microencapsulation in supramolecular gels and the use of profragrances. We report a study on the controlled lactonization of four esters derived from o-coumaric acid. The ester lactonization spontaneously occurs after exposure to solar light, releasing coumarin and the corresponding alcohol. To determine the rate of fragrance release, we compared the reaction in solution and in a supramolecular gel and we demonstrated that the lactonization reaction always occurs slower in the gel. We also studied the more suitable gel for this aim, by comparing the properties of two supramolecular gels obtained with the gelator Boc-L-DOPA(Bn)(2)-OH in a 1:1 ethanol/water mixture in different gelator concentration (0.2% and 1% w/v). The gel prepared with 1% w/v gelator concentration is stronger and less transparent than the other and was used for the profragrances encapsulation. In any case, we obtained a significative reduction of lactonization reaction in gel, compared with the same reaction in solution" |
| Keywords: | L-dopa lactonization low molecular weight gelators profragrances solar light supramolecular gels xerogels; |
| Notes: | "PubMed-not-MEDLINECenciarelli, Fabia Falini, Giuseppe Giuri, Demetra Tomasini, Claudia eng Switzerland 2023/04/27 Gels. 2023 Apr 21; 9(4):350. doi: 10.3390/gels9040350" |
