Bedoukian   RussellIPM   RussellIPM   Piezoelectric Micro-Sprayer


Home
Animal Taxa
Plant Taxa
Semiochemicals
Floral Compounds
Semiochemical Detail
Semiochemicals & Taxa
Synthesis
Control
Invasive spp.
References

Abstract

Guide

Alphascents
Pherobio
InsectScience
E-Econex
Counterpart-Semiochemicals
Print
Email to a Friend
Kindly Donate for The Pherobase

« Previous AbstractOlfactory subsystems in the peripheral olfactory organ of anuran amphibians    Next AbstractPeak assignment in multi-capillary column-ion mobility spectrometry using comparative studies with gas chromatography-mass spectrometry for VOC analysis »

Environ Int


Title:Wood emissions and asthma development: Results from an experimental mouse model and a prospective cohort study
Author(s):Junge KM; Buchenauer L; Elter E; Butter K; Kohajda T; Herberth G; Roder S; Borte M; Kiess W; von Bergen M; Simon JC; Rolle-Kampczyk UE; Lehmann I; Gminski R; Ohlmeyer M; Polte T;
Address:"UFZ - Helmholtz Centre for Environmental Research Leipzig-Halle, Department of Environmental Immunology, Leipzig, Germany. UFZ - Helmholtz Centre for Environmental Research Leipzig-Halle, Department of Environmental Immunology, Leipzig, Germany; Department of Dermatology, Venerology and Allergology, Leipzig University Medical Center, University of Leipzig, Leipzig, Germany. Thunen Institute of Wood Research, Hamburg, Germany. UFZ - Helmholtz Centre for Environmental Research Leipzig-Halle, Department of Molecular Systems Biology, Leipzig, Germany. Children's Hospital, Municipal Hospital 'St. Georg', Leipzig, Germany. University of Leipzig, Hospital for Children and Adolescents - Centre for Pediatric Research, Leipzig, Germany; University of Leipzig, LIFE - Leipzig Research Centre for Civilization Diseases, Leipzig, Germany. UFZ - Helmholtz Centre for Environmental Research Leipzig-Halle, Department of Molecular Systems Biology, Leipzig, Germany; University of Leipzig, Faculty of Life Sciences, Institute of Biochemistry, Leipzig, Germany. Department of Dermatology, Venerology and Allergology, Leipzig University Medical Center, University of Leipzig, Leipzig, Germany. Charite - Universitatsmedizin Berlin, Environmental Epigenetics and Lung Research Group, Berlin, Germany; Berlin Institute of Health (BIH), Molecular Epidemiology, Berlin, Germany. Institute for Infection Prevention and Hospital Epidemiology, Environmental Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany. UFZ - Helmholtz Centre for Environmental Research Leipzig-Halle, Department of Environmental Immunology, Leipzig, Germany; Department of Dermatology, Venerology and Allergology, Leipzig University Medical Center, University of Leipzig, Leipzig, Germany. Electronic address: tobias.polte@ufz.de"
Journal Title:Environ Int
Year:2021
Volume:20210218
Issue:
Page Number:106449 -
DOI: 10.1016/j.envint.2021.106449
ISSN/ISBN:1873-6750 (Electronic) 0160-4120 (Linking)
Abstract:"BACKGROUND: Increased use of renewable resources like sustainably produced wood in construction or for all sorts of long-lived products is considered to contribute to reducing society's carbon footprint. However, as a natural, biological material, wood and wood products emit specific volatile organic compounds (VOCs). Therefore, the evaluation of possible health effects due to wood emissions is of major interest. OBJECTIVES: We investigated the effects of an exposure to multiple wood-related VOCs on asthma development. METHODS: A murine asthma model was used to evaluate possible allergic and inflammatory effects on the lung after short- or long-term and perinatal exposure to pinewood or oriented strand board (OSB). In addition, wood-related VOCs were measured within the German prospective mother-child cohort LINA and their joint effect on early wheezing or asthma development in children until the age of 10 was estimated by Bayesian kernel machine regression (BKMR) stratifying also for family history of atopy (FHA). RESULTS: Our experimental data show that neither pinewood nor OSB emissions even at high total VOC levels and a long-lasting exposure period induce significant inflammatory or asthma-promoting effects in sensitized or non-sensitized mice. Moreover, an exposure during the vulnerable time window around birth was also without effect. Consistently, in our mother-child cohort LINA, an exposure to multiple wood-related VOCs during pregnancy or the first year of life was not associated with early wheezing or asthma development in children independent from their FHA. CONCLUSION: Our findings indicate that emissions from wood and wood products at levels commonly occurring in the living environment do not exert adverse effects concerning wheezing or asthma development"
Keywords:Animals *Asthma/chemically induced Bayes Theorem Mice Prospective Studies *Volatile Organic Compounds/toxicity Wood Asthma Fha LINA cohort Mixture effect Murine asthma model Perinatal exposure Volatile organic compounds Wheezing Wood emission;
Notes:"MedlineJunge, Kristin M Buchenauer, Lisa Elter, Elena Butter, Katja Kohajda, Tibor Herberth, Gunda Roder, Stefan Borte, Michael Kiess, Wieland von Bergen, Martin Simon, Jan C Rolle-Kampczyk, Ulrike E Lehmann, Irina Gminski, Richard Ohlmeyer, Martin Polte, Tobias eng Research Support, Non-U.S. Gov't Netherlands 2021/02/22 Environ Int. 2021 Jun; 151:106449. doi: 10.1016/j.envint.2021.106449. Epub 2021 Feb 18"

 
Back to top
 
Citation: El-Sayed AM 2024. The Pherobase: Database of Pheromones and Semiochemicals. <http://www.pherobase.com>.
© 2003-2024 The Pherobase - Extensive Database of Pheromones and Semiochemicals. Ashraf M. El-Sayed.
Page created on 25-12-2024