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Ann N Y Acad Sci

Title:		Regionally specific occurrence of an active sodefrin variant in the red-bellied newt
Author(s):		Iwata T; Ishizuka Y; Nakada T; Toyoda F; Yamamoto K; Conlon JM; Kikuyama S;
Address:		"Department of Biology, School of Education, Waseda University, Shinjuku-ku, Tokyo, Japan"
Journal Title:		Ann N Y Acad Sci
Year:		2005
Volume:		1040
Issue:
Page Number:		351 - 353
DOI:		10.1196/annals.1327.059
ISSN/ISBN:		0077-8923 (Print) 0077-8923 (Linking)
Abstract:		"Sodefrin (SIPSKDALLK) is a female-attracting pheromone that is secreted by the abdominal gland of the male red-bellied newt. We found that mRNA encoding a sodefrin variant, [Val(8)] sodefrin, is expressed exclusively in specimens captured in the Nara area of Japan. The synthetic peptide was tested for its activity. It attracted females from Nara, but not those from other regions, suggesting that there is a geographic variation in the pheromone molecule and in the responsiveness to the pheromone. Employing an abdominal gland extract and synthetic substrates, the possibility of generation of the putative pheromone, [Val(8)] sodefrin, from the precursor molecule was demonstrated"
Keywords:		"Abdominal Cavity/physiology Animals Exocrine Glands/metabolism Female Genetic Variation Male Oligopeptides/*genetics/*metabolism Protein Processing, Post-Translational Salamandridae/*genetics/*metabolism Sex Attractants/*genetics/*metabolism;"
Notes:		"MedlineIwata, Takeo Ishizuka, Yoko Nakada, Tomoaki Toyoda, Fumiyo Yamamoto, Kazutoshi Conlon, John M Kikuyama, Sakae eng 2005/05/14 Ann N Y Acad Sci. 2005 Apr; 1040:351-3. doi: 10.1196/annals.1327.059"