Title: | Protein folding in hydrophobic-polar lattice model: a flexible ant-colony optimization approach |
Author(s): | Hu XM; Zhang J; Xiao J; Li Y; |
Address: | "Department of Computer Science, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China" |
DOI: | 10.2174/092986608784567465 |
ISSN/ISBN: | 0929-8665 (Print) 0929-8665 (Linking) |
Abstract: | This paper proposes a flexible ant colony (FAC) algorithm for solving protein folding problems based on the hydrophobic-polar square lattice model. Collaborations of novel pheromone and heuristic strategies in the proposed algorithm make it more effective in predicting structures of proteins compared with other state-of-the-art algorithms |
Keywords: | *Algorithms Amino Acids/chemistry Computational Biology/*methods Hydrophobic and Hydrophilic Interactions Protein Conformation *Protein Folding Proteins/*chemistry; |
Notes: | "MedlineHu, Xiao-Min Zhang, Jun Xiao, Jing Li, Yun eng Research Support, Non-U.S. Gov't Netherlands 2008/06/10 Protein Pept Lett. 2008; 15(5):469-77. doi: 10.2174/092986608784567465" |