| Title: | Schistosoma mansoni: a chemoattractive factor released by males and its receptor in females |
| Address: | "Department of Microbiology and Immunology, State University of New York, Brooklyn 11203" |
| ISSN/ISBN: | 0014-4754 (Print) 0014-4754 (Linking) |
| Abstract: | "Chemoattraction between developing (23- to 28-day-old) and adult (10- to 12-week-old) Schistosoma mansoni males and females has been described previously. We report here on in vitro attraction of mature worms to released products of worms of the opposite sex. In the absence of a stimulus worms migrated randomly and did not show any preference in their orientation. Males were not significantly attracted to released products of females. Females exhibited greatest attraction to released products of males, and some attraction to the lipid fraction of released products of males. The aqueous fraction of male-released products slightly repelled females. Prior exposure to released products of males rendered females unresponsive to subsequent exposure, suggesting receptor saturation. These findings have important potential implications for the control of schistosomiasis by intercepting attraction and mating between males and females" |
| Keywords: | Animals Chemical Fractionation Chemoreceptor Cells/*metabolism Chemotactic Factors/*metabolism Female Lipids/physiology Male Mice Movement Schistosoma mansoni/*physiology Sex Attractants/*metabolism; |
| Notes: | "MedlineHaseeb, M A Eveland, L K eng Research Support, Non-U.S. Gov't Switzerland 1991/09/15 Experientia. 1991 Sep 15; 47(9):970-4. doi: 10.1007/BF01929895" |
