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J Feline Med Surg

Title:		A pilot study using synthetic feline facial pheromone for the management of feline idiopathic cystitis
Author(s):		Gunn-Moore DA; Cameron ME;
Address:		"Royal (Dick) School for Veterinary Studies, University of Edinburgh Hospital for Small Animals, Roslin, Midlothian, Scotland, EH25 9RG, UK. Danielle.Gunn-Moore@ed.ac.uk"
Journal Title:		J Feline Med Surg
Year:		2004
Volume:		6
Issue:		3
Page Number:		133 - 138
DOI:		10.1016/j.jfms.2004.01.006
ISSN/ISBN:		1098-612X (Print) 1098-612X (Linking)
Abstract:		"Synthetic feline facial pheromone (FFP) (Feliway; Ceva Animal Health) was assessed for the management of cats with recurrent feline idiopathic cystitis (FIC). Nine of 12 cats completed the randomised, double-blinded, placebo-controlled, crossover pilot study. They had their environment treated daily with either FFP or placebo for 2 months, after which time the treatment groups were reversed. Owners used visual analogue scales to define the severity of their cat's clinical signs and behavioural changes. Five (56%) of the owners stated that their cat's overall health was better when they were using FFP. Four (44%) of the owners noticed no difference between when using the FFP and when using the placebo. While there were no statistical differences between the two treatment groups there was a trend for the cats exposed to FFP to show fewer days with clinical signs of cystitis (FFP total, mean per cat+/-standard deviation, 30, 4.3+/-6.7; placebo 69, 9.9+/-19.1), a lower overall clinical score (1667, 238+/-476; 2009, 287+/-425), a reduced number of episodes of cystitis (9, 1.3+/-2.0; 10, 1.4+/-2.1) and reduced negative behavioural traits (e.g., less aggression and fear) (-128, -18.3+/-65.8; -73, -10.4+/-35.1)"
Keywords:		"Animal Husbandry Animals Cat Diseases/*prevention & control Cats Cross-Over Studies Cystitis/prevention & control/*veterinary Double-Blind Method Eliminative Behavior, Animal/*drug effects Female Male Pain Measurement/veterinary Pheromones/*administration;"
Notes:		"MedlineGunn-Moore, D A Cameron, M E eng Clinical Trial Randomized Controlled Trial Research Support, Non-U.S. Gov't England 2004/05/12 J Feline Med Surg. 2004 Jun; 6(3):133-8. doi: 10.1016/j.jfms.2004.01.006"