| Title: | Pathogen-triggered ethylene signaling mediates systemic-induced susceptibility to herbivory in Arabidopsis |
| Author(s): | Groen SC; Whiteman NK; Bahrami AK; Wilczek AM; Cui J; Russell JA; Cibrian-Jaramillo A; Butler IA; Rana JD; Huang GH; Bush J; Ausubel FM; Pierce NE; |
| Address: | "Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138" |
| ISSN/ISBN: | 1532-298X (Electronic) 1040-4651 (Print) 1040-4651 (Linking) |
| Abstract: | "Multicellular eukaryotic organisms are attacked by numerous parasites from diverse phyla, often simultaneously or sequentially. An outstanding question in these interactions is how hosts integrate signals induced by the attack of different parasites. We used a model system comprised of the plant host Arabidopsis thaliana, the hemibiotrophic bacterial phytopathogen Pseudomonas syringae, and herbivorous larvae of the moth Trichoplusia ni (cabbage looper) to characterize mechanisms involved in systemic-induced susceptibility (SIS) to T. ni herbivory caused by prior infection by virulent P. syringae. We uncovered a complex multilayered induction mechanism for SIS to herbivory. In this mechanism, antiherbivore defenses that depend on signaling via (1) the jasmonic acid-isoleucine conjugate (JA-Ile) and (2) other octadecanoids are suppressed by microbe-associated molecular pattern-triggered salicylic acid (SA) signaling and infection-triggered ethylene signaling, respectively. SIS to herbivory is, in turn, counteracted by a combination of the bacterial JA-Ile mimic coronatine and type III virulence-associated effectors. Our results show that SIS to herbivory involves more than antagonistic signaling between SA and JA-Ile and provide insight into the unexpectedly complex mechanisms behind a seemingly simple trade-off in plant defense against multiple enemies" |
| Keywords: | "Animals Arabidopsis/genetics/*metabolism/*microbiology Arabidopsis Proteins/genetics/metabolism Carboxylic Ester Hydrolases/genetics/metabolism Cyclopentanes/metabolism Ethylenes/*metabolism Gene Expression Regulation, Plant *Herbivory Isoleucine/metaboli;" |
| Notes: | "MedlineGroen, Simon C Whiteman, Noah K Bahrami, Adam K Wilczek, Amity M Cui, Jianping Russell, Jacob A Cibrian-Jaramillo, Angelica Butler, Ian A Rana, Jignasha D Huang, Guo-Hua Bush, Jenifer Ausubel, Frederick M Pierce, Naomi E eng F32 AI069732/AI/NIAID NIH HHS/ P30 CA014051/CA/NCI NIH HHS/ F32AI069732/AI/NIAID NIH HHS/ R37 GM048707/GM/NIGMS NIH HHS/ P30 DK040561/DK/NIDDK NIH HHS/ R37 GM48707/GM/NIGMS NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. England 2013/11/29 Plant Cell. 2013 Nov; 25(11):4755-66. doi: 10.1105/tpc.113.113415. Epub 2013 Nov 27" |
