| Title: | Secondary metabolites and antioxidant capacities of Waldheimia glabra (Decne.) Regel from Nepal |
| Author(s): | Giorgi A; Panseri S; Mattara MS; Andreis C; Chiesa LM; |
| Address: | "Dipartimento di Produzione Vegetale, Universita degli Studi di Milano, Via Celoria 2, I-20133 Milan, Italy. anna.giorgi@unimi.it" |
| ISSN/ISBN: | 1097-0010 (Electronic) 0022-5142 (Linking) |
| Abstract: | "BACKGROUND: The phenolic content, volatile compound fingerprint and antioxidant capacity of Waldheimia glabra (Decne.) Regel (Asteraceae), a wild plant from the Himalayan mountains used in Sherpa religious rituals and in traditional medicine, were determined for the first time to investigate its suitability as a source of natural antioxidants. RESULTS: The total phenolic content and antioxidant capacity of dried and powdered plants from two different altitudes (5000 and 5200 m above sea level) in Khumbu Valley, Nepal were estimated by the Folin-Ciocalteu and 2,2-diphenyl-1-picrylhydrazyl radical methods respectively. The volatile organic compound (VOC) fingerprints from leafing plants (in vivo and in situ VOC sampling) and from dried plant samples were evaluated by headspace solid phase microextraction. The results indicated that W. glabra was a good source of phenolics with antioxidant properties. A correlation between total phenolic content and antioxidant capacity was found (r(2) = 0.9111). Seychellene, a volatile compound that characterises patchouli oil, was detected for the first time in a species of the Asteraceae family. CONCLUSION: Waldheimia glabra was proved to be a good source of antioxidants, partially supporting its traditional uses. Further studies aimed at deepening knowledge on W. glabra bioactivity and its possible uses will be of interest, considering the lack of proper scientific awareness regarding these aspects" |
| Keywords: | Altitude Antioxidants/*analysis/chemistry/metabolism Asteraceae/*chemistry/growth & development/metabolism Bicyclic Monoterpenes Cyclohexane Monoterpenes Cyclohexenes/analysis/chemistry/metabolism Ethnopharmacology Gas Chromatography-Mass Spectrometry Mon; |
| Notes: | "MedlineGiorgi, Annamaria Panseri, Sara Mattara, Manuela S Andreis, Carlo Chiesa, Luca M eng Comparative Study Research Support, Non-U.S. Gov't England 2012/08/21 J Sci Food Agric. 2013 Mar 30; 93(5):1026-34. doi: 10.1002/jsfa.5839. Epub 2012 Aug 20" |
