| Title: | "Regulation of pheromone biosynthesis in the 'Z strain' of the European corn borer, Ostrinia nubilalis" |
| Author(s): | Eltahlawy HS; Buckner JS; Foster SP; |
| Address: | "Department of Entomology, North Dakota State University, Fargo, ND 58105-5346, USA" |
| Journal Title: | Arch Insect Biochem Physiol |
| ISSN/ISBN: | 0739-4462 (Print) 0739-4462 (Linking) |
| Abstract: | "The regulation of pheromone biosynthesis by the neuropeptide PBAN in the Z strain of the European corn borer, Ostrinia nubilalis, was investigated using labeled intermediates. Injection of radiolabeled acetate showed PBAN did not influence the de novo synthesis of saturated fatty acids in the gland. When deuterium-labeled myristic acid was topically applied to the gland, females injected with PBAN produced more labeled pheromone than did control females, indicating that PBAN controls one of the later steps of pheromone biosynthesis. Although more myristic acid was Delta11-desaturated in the gland in the presence of PBAN, this was counterbalanced by less Delta11-desaturation of palmitic acid, indicating that desaturase activity did not change overall. This change in flux of myristic acid through to pheromone was shown to be caused by increased reduction of fatty acid pheromone precursors occurring in the presence of PBAN" |
| Keywords: | "Animals Deuterium Exocrine Glands/drug effects Fatty Acids/biosynthesis Larva/metabolism Moths/*metabolism Myristic Acid/metabolism/pharmacology Neuropeptides/*metabolism/pharmacology Pheromones/*biosynthesis Species Specificity Statistics, Nonparametric;" |
| Notes: | "MedlineEltahlawy, H S Buckner, J S Foster, S P eng Comparative Study Research Support, U.S. Gov't, Non-P.H.S. 2007/04/13 Arch Insect Biochem Physiol. 2007 May; 65(1):29-38. doi: 10.1002/arch.20175" |
