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J Agric Food Chem

Title:		Dispersive micro-solid-phase extraction using mesoporous hybrid materials for simultaneous determination of semivolatile compounds from plant tea by ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry
Author(s):		Cao W; Hu SS; Ye LH; Cao J;
Address:		"College of Material Chemistry and Chemical Engineering, Hangzhou Normal University , 16, Xuelin Street, Xiasha High Education Zone, Hangzhou 310036, China"
Journal Title:		J Agric Food Chem
Year:		2014
Volume:		20140929
Issue:		40
Page Number:		9683 - 9689
DOI:		10.1021/jf5029625
ISSN/ISBN:		1520-5118 (Electronic) 0021-8561 (Linking)
Abstract:		"This report described the use of mesoporous hybrid materials (MHM) in a dispersive micro-solid-phase extraction procedure to extract semivolatile compounds from plant tea that were then analyzed by ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry. Dihydrotanshinone I, tanshinone I, cryptotanshinone, and tanshinone IIA were selected as the model compounds, and the extraction parameters, including mesoporous concentration, extraction time, sample agitation and desorption solvents, were optimized. The interaction with the analytes and the large surface area of the MHM facilitated the adsorption of analytes. The method showed good linearity, with correlation coefficients >0.9980 in the range 0.25-100 ng/mL, and low limits of detection (0.012-0.046 pg). Finally, the recovery values were 91-103% for Danshen tea, 89-102% for Danshen, and 88-96% for tanshinone capsules. The results showed that the proposed method was suitable for the extraction and determination of tanshinones in complex samples"
Keywords:		"Abietanes/analysis Camellia sinensis/*chemistry Chromatography, High Pressure Liquid/*methods Drugs, Chinese Herbal/analysis Food Analysis/instrumentation/methods Limit of Detection Phenanthrenes/analysis Salvia miltiorrhiza Solid Phase Extraction/*method;"
Notes:		"MedlineCao, Wan Hu, Shuai-Shuai Ye, Li-Hong Cao, Jun eng Research Support, Non-U.S. Gov't 2014/09/19 J Agric Food Chem. 2014 Oct 8; 62(40):9683-9. doi: 10.1021/jf5029625. Epub 2014 Sep 29"