| Title: | "The peptide pheromone-inducible conjugation system of Enterococcus faecalis plasmid pCF10: cell-cell signalling, gene transfer, complexity and evolution" |
| Address: | "Department of Microbiology, University of Minnesota, Minneapolis, MN 55455, USA. dunny001@umn.edu" |
| Journal Title: | Philos Trans R Soc Lond B Biol Sci |
| ISSN/ISBN: | 0962-8436 (Print) 1471-2970 (Electronic) 0962-8436 (Linking) |
| Abstract: | "Expression of a large set of gene products required for conjugative transfer of the antibiotic resistance plasmid pCF10 is controlled by cell-cell communication between plasmid-free recipient cells and plasmid-carrying donor cells using a peptide mating pheromone cCF10. Most of the recent experimental analysis of this system has focused on the molecular events involved in initiation of the pheromone response in the donor cells, and on the mechanisms by which the donor cells control self-induction by endogenously produced pheromone. Recently, studies of the molecular machinery of conjugation encoded by the pheromone-inducible genes have been initiated. In addition, the system may serve as a useful bacterial model for addressing the evolution of biological complexity" |
| Keywords: | "Bacterial Proteins/genetics/*physiology Conjugation, Genetic/genetics/*physiology Enterococcus faecalis/genetics/*physiology Gene Expression Regulation, Bacterial/physiology Gene Transfer, Horizontal/genetics/physiology Pheromones/genetics/*physiology Pla;" |
| Notes: | "MedlineDunny, Gary M eng R01 GM049530/GM/NIGMS NIH HHS/ R01 HL051987/HL/NHLBI NIH HHS/ GM49530/GM/NIGMS NIH HHS/ HL51987/HL/NHLBI NIH HHS/ Research Support, N.I.H., Extramural Review England 2007/03/16 Philos Trans R Soc Lond B Biol Sci. 2007 Jul 29; 362(1483):1185-93. doi: 10.1098/rstb.2007.2043" |
