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Biochem Biophys Res Commun

Title:		A role for the Gal11 protein in pheromone-induced transcription in Saccharomyces cerevisiae
Author(s):		Dolan JW; Gatlin JE;
Address:		"Department of Microbiology and Immunology, Medical University of South Carolina, Charleston 29425, USA"
Journal Title:		Biochem Biophys Res Commun
Year:		1995
Volume:		212
Issue:		3
Page Number:		854 - 860
DOI:		10.1006/bbrc.1995.2047
ISSN/ISBN:		0006-291X (Print) 0006-291X (Linking)
Abstract:		"The product of the Saccharomyces cerevisiae GAL11 gene, Gal11p, is required for the proper expression of a wide range of genes including many mating-type-specific genes. In this study Gal11p is shown to have a role in the induction of transcription by pheromone. Basal transcription of an a-specific gene is unaffected by loss of Gal11p but pheromone treatment fails to increase transcription. A haploid-specific gene is shown to retain pheromone-inducibility in the absence of Gal11p but the extent of induction is drastically reduced. Evidence is also presented that suggests the existence of strain differences that can alter the phenotype of gal11 mutants"
Keywords:		"Base Sequence DNA Primers/genetics DNA, Fungal/genetics Fungal Proteins/*genetics Genes, Fungal Genes, Mating Type, Fungal Genes, Regulator Mediator Complex Molecular Sequence Data Mutation Phenotype Pheromones/pharmacology Promoter Regions, Genetic Sacch;"
Notes:		"MedlineDolan, J W Gatlin, J E eng 1995/07/26 Biochem Biophys Res Commun. 1995 Jul 26; 212(3):854-60. doi: 10.1006/bbrc.1995.2047"