Title: | Electrospun Fibrous Nanocomposite Sensing Materials for Monitoring Biomarkers in Exhaled Breath |
Author(s): | Chang YH; Hsieh TH; Hsiao KC; Lin TH; Hsu KH; Wu MC; |
Address: | "Department of Chemical and Materials Engineering, Chang Gung University, Taoyuan 33302, Taiwan. Division of Pediatric Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, Linkou, Taoyuan 33305, Taiwan. Green Technology Research Center, Chang Gung University, Taoyuan 33302, Taiwan" |
ISSN/ISBN: | 2073-4360 (Electronic) 2073-4360 (Linking) |
Abstract: | "Human-exhaled breath mainly contains water, oxygen, carbon dioxide, and endogenous gases closely related to human metabolism. The linear relationship between breath acetone and blood glucose concentration has been revealed when monitoring diabetes patients. Considerable attention has been directed toward developing a highly sensitive volatile organic compounds (VOCs) sensing material that can detect breath acetone. In this study, we propose a tungsten oxide/tin oxide/silver/poly (methyl methacrylate) (WO(3)/SnO(2)/Ag/PMMA) sensing material fabricated using the electrospinning technique. By monitoring the evolution of sensing materials' extinction spectra, low concentrations of acetone vapor can be detected. Moreover, the interfaces between SnO(2) and WO(3) nanocrystals construct n-n junctions, which generate more electron-hole pairs than those without such structure when the light strikes. This helps to improve the sensitivity of sensing materials when they are subjected to acetone surroundings. The established sensing materials (WO(3)/SnO(2)/Ag/PMMA) exhibit a sensing limit of 20 ppm for acetone vapor and show specificity for acetone even in ambient humidity" |
Keywords: | acetone sensor diabetes electrospinning exhaled breath sensors; |
Notes: | "PubMed-not-MEDLINEChang, Yin-Hsuan Hsieh, Ting-Hung Hsiao, Kai-Chi Lin, Ting-Han Hsu, Kai-Hsiang Wu, Ming-Chung eng 111-2628-E-182-001-MY2/National Science and Technology Council, Taiwan/ 111-2221-E-182-040-MY3/National Science and Technology Council, Taiwan/ QZRPD181/Chang Gung University/ CMRPD2L0082/Linkou Chang Gung Memorial Hospital/ BMRPC74/Linkou Chang Gung Memorial Hospital/ Switzerland 2023/04/28 Polymers (Basel). 2023 Apr 10; 15(8):1833. doi: 10.3390/polym15081833" |