| Title: | "PGF2 alpha, PGE2, and sex steroids from the abdominal gland of the male crested newt Triturus carnifex (Laur.)" |
| Address: | "Department of Molecular, Cellular, and Animal Biology, University of Camerino, Italy" |
| DOI: | 10.1016/0090-6980(92)90079-9 |
| ISSN/ISBN: | 0090-6980 (Print) 0090-6980 (Linking) |
| Abstract: | "Prostaglandin F2 alpha (PGF2 alpha), prostaglandin E2 (PGE2), progesterone, androgens, and 17 beta-estradiol in vitro release by the abdominal gland of the crested newt, Triturus carnifex (Laur.), was studied during the prereproductive, reproductive and postreproductive periods. In addition, the in vitro effects of the PGF2 alpha and/or PGE2 on progesterone, androgens and estradiol release by the abdominal gland were evaluated. PGF2 alpha, PGE2 and progesterone release was higher during the reproductive period, and in the same period, PGE2 treatment induced a progesterone increase. PGF2 alpha induced an increase of abdominal gland estradiol release at the end of the reproductive period. These results seemed to confirm the pheromonal role assigned to progesterone, and suggested a PGE2 stimulatory role in inducing progesterone release, even if pheromonal activity of PGF2 alpha and PGE2 cannot be excluded. In addition, PGF2 alpha-dependent estradiol increase at the end of reproduction could be interpreted as a mechanism for interruption of the abdominal gland activity" |
| Keywords: | Abdomen Analysis of Variance Androgens/metabolism Animals Dinoprost/*metabolism/pharmacology Dinoprostone/*metabolism/pharmacology Estradiol/metabolism Female Gonadal Steroid Hormones/*metabolism In Vitro Techniques Male Progesterone/metabolism Reproducti; |
| Notes: | "MedlineCobbetti, A Zerani, M eng Research Support, Non-U.S. Gov't 1992/02/01 Prostaglandins. 1992 Feb; 43(2):101-9. doi: 10.1016/0090-6980(92)90079-9" |
