« Previous AbstractThe origin of the pheromones causing pregnancy block in mice    Next Abstract"One decade of VOCs measurements in Sao Paulo megacity: Composition, variability, and emission evaluation in a biofuel usage context" »

Endokrinologie

Title:		"Suppression of oestrus-inducing pheromone production in the Indian field mouse, Mus booduga Gray, by treatment with an antiandrogen"
Author(s):		Dominic CJ; Pandey SD;
Address:
Journal Title:		Endokrinologie
Year:		1979
Volume:		74
Issue:		1
Page Number:		1 - 5
DOI:
ISSN/ISBN:		0013-7251 (Print) 0013-7251 (Linking)
Abstract:		"The effect of cyproterone acetate (CA) on the production of the male-originating oestrus-inducing pheromone in the Indian field mouse, Mus booduga Gray was investigated. The anoestrus induced in regularly cycling females by unisexual grouping was reversed by exposure to intact males. The majority of male-exposed females returned to oestrus within seven days, with a peak on the fourth-day. By contrast, exposure to CA-treated males failed to induce oestrus in grouped females. Since CA is a potent antiandrogen, the inability of CA-treated males to induce oestrus in females is interpreted as due to the depression of the production of the androgen-dependent pheromone. The results provide evidence in favour of the concept that the oestrus-inducing pheromone in the Indian field mouse is associated with androgens either directly or indirectly through some androgen-dependent gland"
Keywords:		"Animals Cyproterone/*pharmacology Estrus/*drug effects Female Male Mice Pheromones/*physiology Pregnancy Sex Factors Sexual Behavior, Animal/*drug effects;"
Notes:		"MedlineDominic, C J Pandey, S D eng Germany 1979/04/01 Endokrinologie. 1979 Apr; 74(1):1-5"