| Title: | Volatilome and Essential Oil of Ulomoides dermestoides: A Broad-Spectrum Medical Insect |
| Author(s): | Cazares-Samaniego PJ; Castillo CG; Ramos-Lopez MA; Gonzalez-Chavez MM; |
| Address: | "Coordinacion para la Innovacion de la Ciencia y la Tecnologia (CIACYT), Facultad de Medicina, Universidad Autonoma de San Luis Potosi, Sierra Leona #550, Col. Lomas de San Luis, San Luis Potosi C.P. 78210, Mexico. Facultad de Quimica, Universidad Autonoma de Queretaro, Cerro de las Campanas s/n, Col. Las Campanas, Santiago de Queretaro, Queretaro C.P. 76010, Mexico. Facultad de Ciencias Quimicas, Centro de Investigacion y Estudios de Posgrado, Universidad Autonoma de San Luis Potosi, Dr. Manuel Nava Martinez #6, Zona Universitaria, San Luis Potosi C.P. 78210, Mexico" |
| DOI: | 10.3390/molecules26206311 |
| ISSN/ISBN: | 1420-3049 (Electronic) 1420-3049 (Linking) |
| Abstract: | "Ulomoides dermestoides are used as a broad-spectrum medical insect in the alternative treatment of various diseases. Preliminary volatilome studies carried out to date have shown, as the main components, methyl-1,4-benzoquinone, ethyl-1,4-benzoquinone, 1-tridecene, 1-pentadecene, and limonene. This work focused on the production of metabolites and their metabolic variations in U. dermestoides under stress conditions to provide additional valuable information to help better understand the broad-spectrum medical uses. To this end, VOCs were characterized by HS-SPME with PEG and CAR/PDMS fibers, and the first reported insect essential oils were obtained. In HS-SMPE, we found 17 terpenes, six quinones, five alkenes, and four aromatic compounds; in the essential oils, 53 terpenes, 54 carboxylic acids and derivatives, three alkynes, 12 alkenes (1-Pentadecene, EOT1: 77.6% and EOT2: 57.9%), 28 alkanes, nine alkyl disulfides, three aromatic compounds, 19 alcohols, three quinones, and 12 aldehydes were identified. Between both study approaches, a total of 171 secondary metabolites were identified with no previous report for U. dermestoides. A considerable number of the identified metabolites showed previous studies of the activity of pharmacological interest. Therefore, considering the wide variety of activities reported for these metabolites, this work allows a broader vision of the therapeutic potential of U. dermestoides in traditional medicine" |
| Keywords: | "Alcohols/chemistry Aldehydes/chemistry Animals Benzoquinones/chemistry Coleoptera/*chemistry Gas Chromatography-Mass Spectrometry/methods Insecta/*chemistry Oils, Volatile/*chemistry Terpenes/chemistry Volatile Organic Compounds/chemistry Gc-ms Hs-spme Pb;" |
| Notes: | "MedlineCazares-Samaniego, Paulina J Castillo, Claudia G Ramos-Lopez, Miguel A Gonzalez-Chavez, Marco M eng Switzerland 2021/10/24 Molecules. 2021 Oct 19; 26(20):6311. doi: 10.3390/molecules26206311" |
