| Title: | A purge and trap technique to capture volatile compounds combined with comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry to investigate the effect of sulfur-fumigation on Radix Angelicae Dahuricae |
| Author(s): | Cao G; Li Q; Zhang J; Cai H; Cai B; |
| Address: | "College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, People's Republic of China; Research Center of Traditional Chinese Medicine Processing Technology, Zhejiang Chinese Medical University, Hangzhou, 310053, People's Republic of China" |
| ISSN/ISBN: | 1099-0801 (Electronic) 0269-3879 (Linking) |
| Abstract: | "Sulfur-fumigation is known to reduce volatile compounds that are the main active components in herbs used in herbal medicine. We investigated changes in chemical composition between sun-dried and sulfur-fumigated Radix Angelicae Dahuricae using a purge and trap technique to capture volatile compounds, and two-dimensional gas chromatography/time-of-flight mass spectrometry for identification. Using sun-dried Radix Angelicae Dahuricae samples as a reference, the results showed that 73 volatile compounds, including 12 sulfide compounds, were found to be present only in sulfur-fumigated samples. Furthermore, 32 volatile compounds that were found in sun-dried Radix Angelicae Dahuricae samples disappeared after sulfur-fumigation. The proposed method can be applied to accurately discriminate sulfur-fumigated Radix Angelicae Dahuricae from different commercial sources" |
| Keywords: | "Angelica/*chemistry Drugs, Chinese Herbal/*chemistry Fumigation/methods Gas Chromatography-Mass Spectrometry/*methods Plant Roots/chemistry Plants, Medicinal/chemistry Sulfur/chemistry Volatile Organic Compounds/*analysis/chemistry/*isolation & purificati;" |
| Notes: | "MedlineCao, Gang Li, Qinglin Zhang, Jida Cai, Hao Cai, Baochang eng Research Support, Non-U.S. Gov't England 2014/03/13 Biomed Chromatogr. 2014 Sep; 28(9):1167-72. doi: 10.1002/bmc.3146. Epub 2014 Mar 12" |
