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Experientia


Title:[A progesterone-dependent pheromone of the female mouse (author's transl)]
Author(s):Bloch S;
Address:
Journal Title:Experientia
Year:1976
Volume:32
Issue:7
Page Number:937 - 938
DOI: 10.1007/BF02003779
ISSN/ISBN:0014-4754 (Print) 0014-4754 (Linking)
Abstract:"Female mice kept in groups exhibit less oestrous smears than females kept singly. Ovariectomized females have only slightly reduced number of oestrous smears, but ovariectomized females injected with progesterone act on other females like intact ones. It is concluded that a progesterone-dependent pheromone excreted by dioestrous females acts oestrus-depressing on other females. Experiments with female mice, intact, ovariectomized, and ovariectomized and injected with progesterone, kept singly, or in groups, supported the assumption that diestrous females excrete a progesterone-dependent pheromone which has an estrous-depressing effect on other females. The number of estrous days was registered for each subject by means of daily vaginal smears. Estrous days were much fewer in those mice kept in groups, as compared with those kept singly. Results for castrated mice did not differ significantly from those of the intact mice, although the castrated mice injected with progesterone produced the same results as the intact mice. eng"
Keywords:"Animals Diestrus *Estrus/drug effects Female Mice/*physiology Ovary/*physiology Pheromones/*physiology Pregnancy Progesterone/*pharmacology Social Environment Social Isolation *Animals, Laboratory Biology *Castration--side effects Clinical Research *Compa;"
Notes:"MedlineBloch, S ger English Abstract Switzerland 1976/01/01 Experientia. 1976; 32(7):937-8. doi: 10.1007/BF02003779"

 
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