| Title: | Regulation of sleep homeostasis by sexual arousal |
| Author(s): | Beckwith EJ; Geissmann Q; French AS; Gilestro GF; |
| Address: | "Department of Life Sciences, Imperial College London, London, United Kingdom" |
| ISSN/ISBN: | 2050-084X (Electronic) 2050-084X (Linking) |
| Abstract: | "In all animals, sleep pressure is under continuous tight regulation. It is universally accepted that this regulation arises from a two-process model, integrating both a circadian and a homeostatic controller. Here we explore the role of environmental social signals as a third, parallel controller of sleep homeostasis and sleep pressure. We show that, in Drosophila melanogaster males, sleep pressure after sleep deprivation can be counteracted by raising their sexual arousal, either by engaging the flies with prolonged courtship activity or merely by exposing them to female pheromones" |
| Keywords: | "Animals *Arousal *Behavior, Animal Courtship Drosophila melanogaster/*physiology *Homeostasis Male Pheromones/metabolism *Sleep D.melanogaster behaviour computational biology neuroscience sex sleep systems biology;" |
| Notes: | "MedlineBeckwith, Esteban J Geissmann, Quentin French, Alice S Gilestro, Giorgio F eng Wellcome Trust/United Kingdom BB/M003930/1/Biotechnology and Biological Sciences Research Council/United Kingdom BB/J014575/1/Biotechnology and Biological Sciences Research Council/United Kingdom 104931/Z/14/Z/Wellcome Trust/United Kingdom BB/L015129/1/Biotechnology and Biological Sciences Research Council/United Kingdom Research Support, Non-U.S. Gov't England 2017/09/13 Elife. 2017 Sep 12; 6:e27445. doi: 10.7554/eLife.27445" |
