Title: | On the use of Tedlar(R) bags for breath-gas sampling and analysis |
Author(s): | Beauchamp J; Herbig J; Gutmann R; Hansel A; |
Address: | "Ionimed Analytik GmbH, Technikerstrasse 21a, A-6020 Innsbruck, Austria" |
DOI: | 10.1088/1752-7155/2/4/046001 |
ISSN/ISBN: | 1752-7155 (Print) 1752-7155 (Linking) |
Abstract: | "The storage capability of Tedlar(R) bags for gaseous compounds was assessed using on-line proton-transfer-reaction mass spectrometry (PTR-MS). Sample bags were filled with a mixture of volatile organic compounds (VOCs) at known quantities in the ppbv range. The test gas included alcohol, nitrile, aldehyde, ketone, terpene and aromatic compounds. PTR-MS enabled frequent bag-direct measurements of compound abundances over a 70 h storage period. Concentrations of all compounds decreased with bag storage time, with compound-specific decay rates. The most rapid decline in concentration levels was seen for water vapour in the bag, i.e. sample humidity. Such a decrease is particularly relevant for breath-gas samples, where water vapour content is high. Compound losses were attributed to a combination of adsorption to and diffusion through the bag walls. Storage property observations suggest that sample analyses made within 10 h of sampling offer adequate sample authenticity replication. Based on observations, an appropriate bag-cleaning procedure was established and assessed. Results indicated that acceptable bag cleanliness for breath-gas sampling is achievable" |
Notes: | "PubMed-not-MEDLINEBeauchamp, Jonathan Herbig, Jens Gutmann, Rene Hansel, Armin eng England 2008/12/01 J Breath Res. 2008 Dec; 2(4):046001. doi: 10.1088/1752-7155/2/4/046001. Epub 2008 Jul 24" |