| Title: | Selective micro preconcentration of propofol for anesthetic depth monitoring by using seedless electroplated gold as adsorbent |
| Author(s): | Alfeeli B; Zareian-Jahromi MA; Agah M; |
| Address: | "VTMEMS Laboratory, Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA. alfeeli@vt.edu" |
| Journal Title: | Annu Int Conf IEEE Eng Med Biol Soc |
| DOI: | 10.1109/IEMBS.2009.5333868 |
| ISSN/ISBN: | 2375-7477 (Print) 2375-7477 (Linking) |
| Abstract: | "This communication presents selective preconcentration of the anesthetic agent (Propofol) and the elimination of unwanted species from a representative sample of human breath. In this approach, a micro preconcentrator (microPC) consisting of embedded high-aspect-ratio pillars (30 microm x 120 microm chi 240 microm), an outer dimensions of 7 mm x 7 mm (encompass more than 3500 micro pillars), total inner surface area of approximately 10 m(2), and a total inner volume of approximately 6.5 microL was used to selectively preconcentrate Propofol. The microPC has on-chip thermal desorption capability and was coated by electrodeposited gold as an adsorbent material. Experimental evaluations showed successful preconcentration of trace level of Propofol from a mixture containing several volatile organic compounds diluted in water-like solvent (1-propanol) and the efficient removal of non-polar compounds present in the mixture" |
| Keywords: | "1-Propanol/chemistry Adsorption Anesthetics/*pharmacology *Electroplating Electroporation Equipment Design Gold/*chemistry Humans Materials Testing Miniaturization Monitoring, Intraoperative/*instrumentation/methods Optics and Photonics Propofol/*pharmaco;" |
| Notes: | "MedlineAlfeeli, Bassam Zareian-Jahromi, Mohammad A Agah, Masoud eng 2009/12/08 Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:2763-6. doi: 10.1109/IEMBS.2009.5333868" |
