| Title: | Highly Sensitive and Selective Detection of Formaldehyde via Bio-Electrocatalysis over Aldehyde Dehydrogenase |
| Author(s): | Zhang Y; Yu Y; Zhang C; Song N; Guo Z; Liang M; |
| Address: | "Experimental Center of Advanced Materials, School of Materials Science & Engineering, Beijing Institute of Technology, Beijing100081, China. Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing100085, China" |
| DOI: | 10.1021/acs.analchem.2c03632 |
| ISSN/ISBN: | 1520-6882 (Electronic) 0003-2700 (Linking) |
| Abstract: | "Formaldehyde (HCHO), as one of the prominent indoor pollutants, causes many health-related problems. Although the detection of HCHO is a widespread concern and a variety of detection methods have been continuously developed, the volatile organic chemical (VOC) interference remains to be solved. Here, we report a highly sensitive and selective method for HCHO detection, relying on the selective electrochemical oxidation of formaldehyde catalyzed by aldehyde dehydrogenases (ALDHs) on a Cu electrode. The detection signal exhibits a standard power law relationship against the analytes with a broad detection range of 10(-5)-10(-15) M and a limit of detection (LOD) of 1.46 x 10(-15) M, far below the indoor safe exposure limit (about 10(-9) M) for formaldehyde. In comparison to the standard spectrophotometry method, the ALDH-based electrochemical method shows a much high specificity to formaldehyde among common VOCs, such as benzene, toluene, and xylene. This simple yet effective detection technique opens up a new path for developing advanced formaldehyde sensors with high sensitivity and selectivity" |
| Keywords: | "*Air Pollution, Indoor/analysis Environmental Monitoring/methods Aldehyde Dehydrogenase Formaldehyde/analysis *Volatile Organic Compounds/analysis *Air Pollutants/analysis;" |
| Notes: | "MedlineZhang, Yinuo Yu, Yue Zhang, Changbin Song, Ningning Guo, Zhanjun Liang, Minmin eng Research Support, Non-U.S. Gov't 2022/11/03 Anal Chem. 2022 Nov 15; 94(45):15827-15831. doi: 10.1021/acs.analchem.2c03632. Epub 2022 Nov 2" |
