« Previous AbstractEstimating subcooled liquid vapor pressures and octanol-air partition coefficients of polybrominated diphenyl ethers and their temperature dependence    Next AbstractNectar yeasts enhance the interaction between Clematis akebioides and its bumblebee pollinator »

J Microbiol

Title:		Biocontrol activity of volatile organic compounds from Streptomyces alboflavus TD-1 against Aspergillus flavus growth and aflatoxin production
Author(s):		Yang M; Lu L; Pang J; Hu Y; Guo Q; Li Z; Wu S; Liu H; Wang C;
Address:		"State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Engineering and Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, P. R. China. State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Engineering and Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, P. R. China. clw123@tust.edu.cn"
Journal Title:		J Microbiol
Year:		2019
Volume:		20190506
Issue:		5
Page Number:		396 - 404
DOI:		10.1007/s12275-019-8517-9
ISSN/ISBN:		1976-3794 (Electronic) 1225-8873 (Linking)
Abstract:		"Aspergillus flavus is a saprophytic fungus that contaminates crops with carcinogenic aflatoxin. In the present work, the antifungal effects of volatile organic compounds (VOCs) from Streptomyces alboflavus TD-1 against A. flavus were investigated. VOCs from 8-day-old wheat bran culture of S. alboflavus TD-1 displayed strong inhibitory effects against mycelial growth, sporulation, and conidial germination of A. flavus. Severely misshapen conidia and hyphae of A. flavus were observed by scanning electron microscopy after exposure to VOCs for 6 and 12 h, respectively. Rhodamine 123 staining of mitochondria indicated that mitochondria may be a legitimate antifungal target of the VOCs from S. alboflavus TD-1. Furthermore, the VOCs effectively inhibited aflatoxin B1 production by downregulating genes involved in aflatoxin biosynthesis. Dimethyl trisulfide and benzenamine may play important roles in the suppression of A. flavus growth and production of aflatoxin. The results indicate that VOCs from S. alboflavus TD-1 have tremendous potential to be developed as a useful bio-pesticide for controlling A. flavus"
Keywords:		"Aflatoxin B1/*biosynthesis/genetics Antifungal Agents/metabolism/*pharmacology Aspergillus flavus/*growth & development/*metabolism Biological Control Agents/metabolism/*pharmacology Down-Regulation/drug effects Gene Expression Regulation, Fungal Membrane;"
Notes:		"MedlineYang, Mingguan Lu, Laifeng Pang, Jing Hu, Yiling Guo, Qingbin Li, Zhenjing Wu, Shufen Liu, Huanhuan Wang, Changlu eng Korea (South) 2019/05/08 J Microbiol. 2019 May; 57(5):396-404. doi: 10.1007/s12275-019-8517-9. Epub 2019 May 6"