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Crit Rev Anal Chem

Title:		"GC-Based Techniques for Breath Analysis: Current Status, Challenges, and Prospects"
Author(s):		Xu M; Tang Z; Duan Y; Liu Y;
Address:		"a College of Chemistry, Sichuan University , Chengdu , China. b Research Center of Analytical Instrumentation, Key Laboratory of Bio-resource and Eco-environment, Ministry of Education, College of Life Sciences, Sichuan University , Chengdu , China. c Analytical and Testing Center, Sichuan University , Chengdu , China"
Journal Title:		Crit Rev Anal Chem
Year:		2016
Volume:		20151103
Issue:		4
Page Number:		291 - 304
DOI:		10.1080/10408347.2015.1055550
ISSN/ISBN:		1547-6510 (Electronic) 1040-8347 (Linking)
Abstract:		"Breath analysis is a noninvasive diagnostic method that profiles a person's physical state by volatile organic compounds in the breath. It has huge potential in the field of disease diagnosis. In order to offer opportunities for practical applications, various GC-based techniques have been investigated for on-line breath analysis since GC is the most preferred technique for mixed gas separation. This article reviews the development of breath analysis and GC-based techniques in basic breath research, involving sampling methods, preconcentration methods, conventional GC-based techniques, and newly developed GC techniques for breath analysis. The combination of GC and newly developed detection techniques takes advantages of the virtues of each. In addition, portable GC or micro GC are poised to become field GC-based techniques in breath analysis. Challenges faced in GC-based techniques for breath analysis are discussed candidly. Effective cooperation of experts from different fields is urgent to promote the development of breath analysis"
Keywords:		"Breath Tests/*methods Chromatography, Gas/*methods Humans Volatile Organic Compounds/*analysis Breath analysis micro GC system portable GC system resistive heating volatile organic compounds;"
Notes:		"MedlineXu, Mingjun Tang, Zhentao Duan, Yixiang Liu, Yong eng Review 2015/11/04 Crit Rev Anal Chem. 2016 Jul 3; 46(4):291-304. doi: 10.1080/10408347.2015.1055550. Epub 2015 Nov 3"