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Soc Cogn Affect Neurosci

Title:		Androstadienone modulates human aggression in a sex-dependent manner
Author(s):		Wu Y; Wei R; Nan Y; Hu Y; Ye Y;
Address:		"Department of Applied Social Sciences, Hong Kong Polytechnic University, Hung Hom, Hong Kong, China. Research Institute for Sports Science and Technology, Hong Kong Polytechnic University, Hung Hom, Hong Kong, China. School of Psychology and Cognitive Science, East China Normal University, Shanghai 200062, China. Shanghai Key Laboratory of Mental Health and Psychological Crisis Intervention, East China Normal University, Shanghai 200062, China. Institute of Psychology, School of Public Affairs, Xiamen University, Xiamen 361005, China"
Journal Title:		Soc Cogn Affect Neurosci
Year:		2023
Volume:		18
Issue:		1
Page Number:		-
DOI:		10.1093/scan/nsad006
ISSN/ISBN:		1749-5024 (Electronic) 1749-5016 (Print) 1749-5016 (Linking)
Abstract:		"Chemosensory communication is ubiquitous in human social interaction. Androstadienone is a potential candidate human sex pheromone that is associated with social dominance and competition. The aim of the present study was to investigate the effects of androstadienone on aggression. We specifically distinguished two types of aggression, namely proactive and reactive aggression. Two hundred and six male and female participants received either androstadienone or a control carrier in a double-blind, placebo-controlled, between-participants design. Participants performed two aggression tasks, one on reactive aggression and the other on proactive aggression, while they were exposed to the olfactory stimuli. The results revealed that for men, smelling androstadienone reduced both reactive and proactive aggression, whereas it increased reactive aggression in women. These effects were present despite the olfactory stimuli not being explicitly discriminable. These findings provide direct evidence that androstadienone modulates human aggression in a sex-dependent manner"
Keywords:		"Humans Male Female *Pheromones, Human/pharmacology *Smell Aggression androstadienone chemosignaling dominance sexual dimorphism;"
Notes:		"MedlineWu, Yin Wei, Ran Nan, Yu Hu, Yang Ye, Yuting eng Randomized Controlled Trial Research Support, Non-U.S. Gov't England 2023/02/16 Soc Cogn Affect Neurosci. 2023 Feb 25; 18(1):nsad006. doi: 10.1093/scan/nsad006"